6-Phenyl-2-thiouracil

Name: 6-Phenyl-2-thiouracil
Brand: Vaqora Chemicals
SKU: VQ-032606

About 6-Phenyl-2-thiouracil

6-Phenyl-2-thiouracil is a process intermediate or related compound of Propylthiouracil carrying the CAS registry number 36822-11-4. Its molecular formula is C10H8N2OS and its molecular weight is 204.25 g/mol. The IUPAC name is 6-phenyl-2-sulfanylidene-1H-pyrimidin-4-one. Alternative names: 6-Phenylthiouracil and 2-mercapto-6-phenylpyrimidin-4-ol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Propylthiouracil, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 6-Phenyl-2-thiouracil is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Propylthiouracil

View every impurity, metabolite and intermediate we list for Propylthiouracil.

Propylthiouracil impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Phenyl-2-thiouracil
Catalogue No.	VQ-032606
CAS Number	36822-11-4
IUPAC name	6-phenyl-2-sulfanylidene-1H-pyrimidin-4-one
Molecular formula	C₁₀H₈N₂OS
Molecular weight	204.25 g/mol
Exact mass	204.0357
HSN code	2933
InChIKey	XEKNACRTWJHOCE-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)C2=CC(=O)NC(=S)N2
PubChem CID	697057

Physical properties
Physical form	Solid
LogP (XLogP3)	1.3
H-bond donors / acceptors	2 / 2
TPSA	73.2 Å²
Synonyms	6-Phenylthiouracil, 2-mercapto-6-phenylpyrimidin-4-ol, 4-Hydroxy-2-mercapto-6-phenylpyrimidine, 6-Phenyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, 2-Mercapto-6-phenylpyrimidin-4-one, 2-Mercapto-6-phenyl-pyrimidin-4-ol, 4(1H)-Pyrimidinone, 2,3-dihydro-6-phenyl-2-thioxo-, 6-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one, 2-mercapto-6-phenylpyrimidin-4(3H)-one, 6-phenyl-2-sulfanylpyrimidin-4-ol, 2,3-dihydro-2-thioxo-6-phenylpyrimidin-4(1H)-one, 6-phenyl-2-sulfanylpyrimidin-4(1H)-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Phenyl-2-thiouracil?

The CAS Registry Number of 6-Phenyl-2-thiouracil is 36822-11-4. It is also known as 6-Phenylthiouracil, 2-mercapto-6-phenylpyrimidin-4-ol, 4-Hydroxy-2-mercapto-6-phenylpyrimidine.

What is the molecular formula and molecular weight of 6-Phenyl-2-thiouracil?

6-Phenyl-2-thiouracil has the molecular formula C10H8N2OS and a molecular weight of 204.25 g/mol. Its IUPAC name is 6-phenyl-2-sulfanylidene-1H-pyrimidin-4-one.

What is 6-Phenyl-2-thiouracil used for?

6-Phenyl-2-thiouracil is supplied as a characterised reference material related to Propylthiouracil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Phenyl-2-thiouracil can I order?

We supply 6-Phenyl-2-thiouracil, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Phenyl-2-thiouracil?

Yes. Every lot of 6-Phenyl-2-thiouracil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Phenyl-2-thiouracil be shipped internationally?

Yes. 6-Phenyl-2-thiouracil is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.