4-Fluoro-2-methoxy-5-nitroaniline (CAS 1075705-01-9) chemical structure

VAQORA

API ImpuritiesReference StandardAvailable on request

4-Fluoro-2-methoxy-5-nitroaniline

Name: 4-Fluoro-2-methoxy-5-nitroaniline
Brand: Vaqora Chemicals
SKU: VQ-038815

Synonyms: 4-Fluoro-5-nitro-o-anisidine · 2-Amino-5-fluoro-4-nitroanisole · Benzenamine, 4-fluoro-2-methoxy-5-nitro- · 4-Fluoro-2-methoxy-5-ni

CAS No.1075705-01-9

FormulaC₇H₇FN₂O₃

Mol. weight186.14

Catalogue No.VQ-038815

PurityReference Standard

HSN38229090

4-Fluoro-2-methoxy-5-nitroaniline (CAS 1075705-01-9) – Osimertinib impurity standard. C7H7FN2O3, MW 186.14. Vaqora Chemicals: COA, global shipping.

Pack sizesPrice on quotation · bulk available

10 mg

25 mg

50 mg

100 mg

Bulk / custom pack · kg to MT

Enquire

Batch COA with every lot

16-section GHS SDS

Export to 120+ countries

DG-compliant packing

About 4-Fluoro-2-methoxy-5-nitroaniline

4-Fluoro-2-methoxy-5-nitroaniline (CAS 1075705-01-9) is an impurity of Osimertinib offered by Vaqora Chemicals. The compound has the formula C7H7FN2O3, corresponding to a molecular weight of 186.14 g/mol. Common synonyms include 4-Fluoro-5-nitro-o-anisidine and 2-Amino-5-fluoro-4-nitroanisole.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Osimertinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Fluoro-2-methoxy-5-nitroaniline in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Fluoro-2-methoxy-5-nitroaniline
Catalogue No.	VQ-038815
CAS Number	1075705-01-9
IUPAC name	4-fluoro-2-methoxy-5-nitroaniline
Molecular formula	C₇H₇FN₂O₃
Molecular weight	186.14 g/mol
Exact mass	186.0441
Grade	Reference Standard
HSN code	38229090
InChIKey	FYSIGSQCZXQTIH-UHFFFAOYSA-N
SMILES	COC1=CC(=C(C=C1N)[N+](=O)[O-])F
PubChem CID	57429072

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	1 / 5
TPSA	81.1 Å²
Synonyms	4-Fluoro-5-nitro-o-anisidine, 2-Amino-5-fluoro-4-nitroanisole, Benzenamine, 4-fluoro-2-methoxy-5-nitro-, 4-Fluoro-2-methoxy-5-ni, 2-Methoxy-4-fluoro-5-nitroaniline, CS-B0928, 4-Fluoro-2-methoxy-5-nitrobenzenamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Fluoro-2-methoxy-5-nitroaniline?

The CAS Registry Number of 4-Fluoro-2-methoxy-5-nitroaniline is 1075705-01-9. It is also known as 4-Fluoro-5-nitro-o-anisidine, 2-Amino-5-fluoro-4-nitroanisole, Benzenamine, 4-fluoro-2-methoxy-5-nitro-.

What is the molecular formula and molecular weight of 4-Fluoro-2-methoxy-5-nitroaniline?

4-Fluoro-2-methoxy-5-nitroaniline has the molecular formula C7H7FN2O3 and a molecular weight of 186.14 g/mol. Its IUPAC name is 4-fluoro-2-methoxy-5-nitroaniline.

What is 4-Fluoro-2-methoxy-5-nitroaniline used for?

4-Fluoro-2-methoxy-5-nitroaniline is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Fluoro-2-methoxy-5-nitroaniline can I order?

We supply 4-Fluoro-2-methoxy-5-nitroaniline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Fluoro-2-methoxy-5-nitroaniline?

Yes. Every lot of 4-Fluoro-2-methoxy-5-nitroaniline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Fluoro-2-methoxy-5-nitroaniline be shipped internationally?

Yes. 4-Fluoro-2-methoxy-5-nitroaniline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.