4-Hydroxy Diclofenac-d4

Name: 4-Hydroxy Diclofenac-d4
Brand: Vaqora Chemicals
SKU: VQ-036679

About 4-Hydroxy Diclofenac-d4

Listed under CAS 254762-27-1, 4-Hydroxy Diclofenac-d4 is a stable isotope labelled analogue related to Diclofenac available from Vaqora Chemicals. The compound has the formula C14H11Cl2NO3, corresponding to a molecular weight of 316.2 g/mol. The IUPAC name is 2-[2,3,4,5-tetradeuterio-6-(2,6-dichloro-4-hydroxyanilino)phenyl]acetic acid. It is also known as 4'-Hydroxy Diclofenac-D4 (Major) or 4Hydroxy Diclofenac-D4 (Major).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Hydroxy Diclofenac-d4 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Diclofenac

View every impurity, metabolite and intermediate we list for Diclofenac.

Diclofenac impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy Diclofenac-d4
Catalogue No.	VQ-036679
CAS Number	254762-27-1
IUPAC name	2-[2,3,4,5-tetradeuterio-6-(2,6-dichloro-4-hydroxyanilino)phenyl]acetic acid
Molecular formula	C₁₄H₁₁Cl₂NO₃
Molecular weight	316.2 g/mol
Exact mass	315.0367
Grade	Reference Standard
HSN code	38229090
InChIKey	KGVXVPRLBMWZLG-RHQRLBAQSA-N
SMILES	[2H]C1=C(C(=C(C(=C1[2H])CC(=O)O)NC2=C(C=C(C=C2Cl)O)Cl)[2H])[2H]
PubChem CID	10805325

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	3 / 4
TPSA	69.6 Å²
Synonyms	4'-Hydroxy Diclofenac-D4 (Major), 4Hydroxy Diclofenac-D4 (Major), TMIJ-0128, [2-(2,6-Dichloro-4-hydroxyanilino)(~2~H_4_)phenyl]acetic acid, 2-[2,3,4,5-tetradeuterio-6-(2,6-dichloro-4-hydroxy-anilino)phenyl]acetic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy Diclofenac-d4?

The CAS Registry Number of 4-Hydroxy Diclofenac-d4 is 254762-27-1. It is also known as 4'-Hydroxy Diclofenac-D4 (Major), 4Hydroxy Diclofenac-D4 (Major), TMIJ-0128.

What is the molecular formula and molecular weight of 4-Hydroxy Diclofenac-d4?

4-Hydroxy Diclofenac-d4 has the molecular formula C14H11Cl2NO3 and a molecular weight of 316.2 g/mol. Its IUPAC name is 2-[2,3,4,5-tetradeuterio-6-(2,6-dichloro-4-hydroxyanilino)phenyl]acetic acid.

What is 4-Hydroxy Diclofenac-d4 used for?

4-Hydroxy Diclofenac-d4 is supplied as a characterised reference material related to Diclofenac. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy Diclofenac-d4 can I order?

We supply 4-Hydroxy Diclofenac-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy Diclofenac-d4?

Yes. Every lot of 4-Hydroxy Diclofenac-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy Diclofenac-d4 be shipped internationally?

Yes. We export 4-Hydroxy Diclofenac-d4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.