4-Hydroxy Ibrutinib

Name: 4-Hydroxy Ibrutinib
Brand: Vaqora Chemicals
SKU: VQ-048600

About 4-Hydroxy Ibrutinib

4-Hydroxy Ibrutinib (CAS 1288339-18-3) is a metabolite or degradation product of Ibrutinib offered by Vaqora Chemicals. With the molecular formula C25H24N6O3, it has a molar mass of 456.5 g/mol. The IUPAC name is 1-[3-[4-amino-3-[4-(4-hydroxyphenoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Ibrutinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 4-Hydroxy Ibrutinib in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ibrutinib

View every impurity, metabolite and intermediate we list for Ibrutinib.

Ibrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Hydroxy Ibrutinib
Catalogue No.	VQ-048600
CAS Number	1288339-18-3
IUPAC name	1-[3-[4-amino-3-[4-(4-hydroxyphenoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
Molecular formula	C₂₅H₂₄N₆O₃
Molecular weight	456.5 g/mol
Exact mass	456.191
Grade	Reference Standard
HSN code	38229090
InChIKey	HJAGSCLKIGHKCE-UHFFFAOYSA-N
SMILES	C=CC(=O)N1CCCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=C(C=C5)O)N
PubChem CID	58223274

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	2 / 7
TPSA	119 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Hydroxy Ibrutinib?

The CAS Registry Number of 4-Hydroxy Ibrutinib is 1288339-18-3.

What is the molecular formula and molecular weight of 4-Hydroxy Ibrutinib?

4-Hydroxy Ibrutinib has the molecular formula C25H24N6O3 and a molecular weight of 456.5 g/mol. Its IUPAC name is 1-[3-[4-amino-3-[4-(4-hydroxyphenoxy)phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one.

What is 4-Hydroxy Ibrutinib used for?

4-Hydroxy Ibrutinib is supplied as a characterised reference material related to Ibrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Hydroxy Ibrutinib can I order?

We supply 4-Hydroxy Ibrutinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Hydroxy Ibrutinib?

Yes. Every lot of 4-Hydroxy Ibrutinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Hydroxy Ibrutinib be shipped internationally?

Yes. We export 4-Hydroxy Ibrutinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.