(2R,3R)-4-((4-Chlorophenyl)amino)-2,3-dihydroxy-4-oxobutanoic acid
- CAS
- 17447-35-7
- Formula
- C10H10ClNO5
- MW
- 259.64 g/mol
VQ-048603
Impurity reference standards
Ibrutinib impurities & reference standards
Characterised Ibrutinib impurities, degradation products and related compounds for analytical method development, validation, QC release and regulatory filings.
88reference materials
2nitrosamine impurities
2isotope-labelled
COAHPLC · NMR · MS on request
Parent API: Ibrutinib WS
936563-96-1 · C25H24N6O2
![(R)-1-(3-(3-(4-Phenoxyphenyl)-4-((triphenyl-l5-phosphanylidene)amino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one](/media/pack/r-1-3-3-4-phenoxyphenyl-4-triphenyl-l5-phosphanylideneamino-1h-pyrazolo34-dpyrimidin-1.svg?v=3)
(R)-1-(3-(3-(4-Phenoxyphenyl)-4-((triphenyl-l5-phosphanylidene)amino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one
- CAS
- 2064175-44-4
- Formula
- C43H37N6O2P
- MW
- 700.8 g/mol
VQ-031124
![(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Dihydrochloride chemical structure](/media/structures/ZGTOUEKDPROJPB-UHFFFAOYSA-N.svg)
(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Dihydrochloride
- CAS
- 1701403-10-2
- Formula
- C22H24Cl2N6O
- MW
- 459.4 g/mol
VQ-031122
![(R)-N-(3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-1,1,1-triphenyl-l5-phosphanimine chemical structure](/media/structures/CUAUFVPNQHCTHO-WJOKGBTCSA-N.svg)
(R)-N-(3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-1,1,1-triphenyl-l5-phosphanimine
- CAS
- 2064175-43-3
- Formula
- C40H35N6OP
- MW
- 646.7 g/mol
VQ-043684
1 Butyl 3 4 phenoxyphenyl 1h pyrazolo 3 4 d pyrimidin 4 amine
- CAS
- 2213398-77-5
- Formula
- C21H21N5O
- MW
- 359.4 g/mol
VQ-048607
1 Isopropyl 3 4 phenoxyphenyl 1h pyrazolo 3 4 d pyrimidin 4 amine
- CAS
- 2803461-05-2
- Formula
- C20H19N5O
- MW
- 345.4 g/mol
VQ-048606
![1-((R)-3-(4-Amino-3-(4-(phenoxy-D5)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one chemical structure](/media/structures/NWKPMPRXJGMTKQ-ROSSWGEHSA-N.svg)
1-((R)-3-(4-Amino-3-(4-(phenoxy-D5)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one
- CAS
- 2068022-09-1
- Formula
- C25H26N6O4
- MW
- 479.5 g/mol
VQ-037620
1,1-Dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene
- CAS
- 330792-69-3
- Formula
- C17H12N2O2
- MW
- 276.29 g/mol
VQ-026098
![4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine chemical structure](/media/structures/HQAIUXZORKJOJY-UHFFFAOYSA-N.svg)
5-Amino-1-methyl-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
- CAS
- 1516569-46-2
- Formula
- C17H14N4O
- MW
- 290.32 g/mol
VQ-031127
5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carboxamide
- CAS
- 2782705-43-3
- Formula
- C16H14N4O2
- MW
- 294.31 g/mol
VQ-048605
Chloro Propanyl Dimer Impurity of Ibrutinib (PCI-7547)
- CAS
- 2031255-23-7
- Formula
- C50H48N12O4
- MW
- 881 g/mol
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FAQs — Ibrutinib impurities
Which Ibrutinib impurities do you supply?
We list 88 Ibrutinib-related reference materials, including process impurities, degradation products, nitrosamine impurities, stable-isotope-labelled standards and related compounds. Each is supplied with a COA, and characterisation data (HPLC, 1H-NMR, MS, IR) can be provided on request.
What are Ibrutinib impurity standards used for?
They are used for analytical method development and validation, impurity identification and quantification, forced-degradation and stability studies, and to support ANDA, DMF and other regulatory submissions under ICH Q3A/Q3B (and ICH M7 for mutagenic impurities).
Can you synthesise a Ibrutinib impurity that is not listed?
Yes. Our custom synthesis service can prepare and characterise unlisted impurities, metabolites and labelled analogues from milligram to gram scale. Share the structure or name and required quantity for a quotation.
Request Ibrutinib impurity standards
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