4-(Hydroxymethyl)-1,3-benzodioxole

Name: 4-(Hydroxymethyl)-1,3-benzodioxole
Brand: Vaqora Chemicals
SKU: VQ-038879

About 4-(Hydroxymethyl)-1,3-benzodioxole

Listed under CAS 769-30-2, 4-(Hydroxymethyl)-1,3-benzodioxole is a metabolite or degradation product of Tadalafil available from Vaqora Chemicals. Formula C8H8O3, molecular weight 152.15 g/mol. The IUPAC name is 1,3-benzodioxol-4-ylmethanol. Alternative names: (1,3-dioxaindan-4-yl)methanol and benzo[d][1,3]dioxol-4-ylmethanol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Tadalafil, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-(Hydroxymethyl)-1,3-benzodioxole is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tadalafil

View every impurity, metabolite and intermediate we list for Tadalafil.

Tadalafil impurities

Specifications & identifiers

Chemical identifiers
Product name	4-(Hydroxymethyl)-1,3-benzodioxole
Catalogue No.	VQ-038879
CAS Number	769-30-2
IUPAC name	1,3-benzodioxol-4-ylmethanol
Molecular formula	C₈H₈O₃
Molecular weight	152.15 g/mol
Exact mass	152.0473
Grade	Reference Standard
HSN code	38229090
InChIKey	XVCMMPXFVAHHQN-UHFFFAOYSA-N
SMILES	C1OC2=CC=CC(=C2O1)CO
PubChem CID	2776187

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	1 / 3
TPSA	38.7 Å²
Synonyms	(1,3-dioxaindan-4-yl)methanol, benzo[d][1,3]dioxol-4-ylmethanol, 1,3-Benzodioxole-4-methanol, Benzo[1,3]dioxol-4-yl-methanol, (2H-1,3-Benzodioxol-4-yl)methanol, (benzo[d][1,3]dioxol-7-yl)methanol, 2H-benzo[d]1,3-dioxolen-4-ylmethan-1-ol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-(Hydroxymethyl)-1,3-benzodioxole?

The CAS Registry Number of 4-(Hydroxymethyl)-1,3-benzodioxole is 769-30-2. It is also known as (1,3-dioxaindan-4-yl)methanol, benzo[d][1,3]dioxol-4-ylmethanol, 1,3-Benzodioxole-4-methanol.

What is the molecular formula and molecular weight of 4-(Hydroxymethyl)-1,3-benzodioxole?

4-(Hydroxymethyl)-1,3-benzodioxole has the molecular formula C8H8O3 and a molecular weight of 152.15 g/mol. Its IUPAC name is 1,3-benzodioxol-4-ylmethanol.

What is 4-(Hydroxymethyl)-1,3-benzodioxole used for?

4-(Hydroxymethyl)-1,3-benzodioxole is supplied as a characterised reference material related to Tadalafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-(Hydroxymethyl)-1,3-benzodioxole can I order?

We supply 4-(Hydroxymethyl)-1,3-benzodioxole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-(Hydroxymethyl)-1,3-benzodioxole?

Yes. Every lot of 4-(Hydroxymethyl)-1,3-benzodioxole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-(Hydroxymethyl)-1,3-benzodioxole be shipped internationally?

Yes. 4-(Hydroxymethyl)-1,3-benzodioxole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.