41-O-Demethylrapamycin

Name: 41-O-Demethylrapamycin
Brand: Vaqora Chemicals
SKU: VQ-033872

About 41-O-Demethylrapamycin

41-O-Demethylrapamycin is a metabolite or degradation product of Rapamycin carrying the CAS registry number 142382-16-9. The compound has the formula C50H77NO13, corresponding to a molecular weight of 900.1 g/mol. Common synonyms include Rapamycin, 41-O-demethyl-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Rapamycin, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 41-O-Demethylrapamycin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Rapamycin

View every impurity, metabolite and intermediate we list for Rapamycin.

Rapamycin impurities

Specifications & identifiers

Chemical identifiers
Product name	41-O-Demethylrapamycin
Catalogue No.	VQ-033872
CAS Number	142382-16-9
IUPAC name	(1R,9S,12S,15R,16Z,18R,19R,21R,23S,24Z,26Z,28Z,30S,32S,35R)-12-[(2R)-1-[(1S,3R,4R)-3,4-dihydroxycyclohexyl]propan-2-yl]-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Molecular formula	C₅₀H₇₇NO₁₃
Molecular weight	900.1 g/mol
Exact mass	899.5395
Grade	Reference Standard
HSN code	38229090
InChIKey	RGRYVHKBWYXMGM-RRAIHGQLSA-N
SMILES	C[C@@H]1CC[C@H]2C[C@@H](/C(=C\C=C/C=C\[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C\[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)O)O)C)/C)O)OC)C)C)/C)OC
PubChem CID	155487647

Physical properties
Physical form	Solid
LogP (XLogP3)	5.5
H-bond donors / acceptors	4 / 13
TPSA	206 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 41-O-Demethylrapamycin?

The CAS Registry Number of 41-O-Demethylrapamycin is 142382-16-9. It is also known as Rapamycin, 41-O-demethyl-.

What is the molecular formula and molecular weight of 41-O-Demethylrapamycin?

41-O-Demethylrapamycin has the molecular formula C50H77NO13 and a molecular weight of 900.1 g/mol.

What is 41-O-Demethylrapamycin used for?

41-O-Demethylrapamycin is supplied as a characterised reference material related to Rapamycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 41-O-Demethylrapamycin can I order?

We supply 41-O-Demethylrapamycin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 41-O-Demethylrapamycin?

Yes. Every lot of 41-O-Demethylrapamycin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 41-O-Demethylrapamycin be shipped internationally?

Yes. We export 41-O-Demethylrapamycin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.