7-O-Demethyl Rapamycin

Name: 7-O-Demethyl Rapamycin
Brand: Vaqora Chemicals
SKU: VQ-033867

About 7-O-Demethyl Rapamycin

7-O-Demethyl Rapamycin (CAS 151519-50-5) is a metabolite or degradation product of Rapamycin offered by Vaqora Chemicals. Formula C50H77NO13, molecular weight 900.1 g/mol. It is also known as 7-O-Demethylsirolimus or 16-O-Demethylrapamycin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Rapamycin, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 7-O-Demethyl Rapamycin in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Rapamycin

View every impurity, metabolite and intermediate we list for Rapamycin.

Rapamycin impurities

Specifications & identifiers

Chemical identifiers
Product name	7-O-Demethyl Rapamycin
Catalogue No.	VQ-033867
CAS Number	151519-50-5
IUPAC name	(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18,30-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Molecular formula	C₅₀H₇₇NO₁₃
Molecular weight	900.1 g/mol
Exact mass	899.5395
Grade	Reference Standard
HSN code	38229090
InChIKey	ZHYGVVKSAGDVDY-QQQXYHJWSA-N
SMILES	C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)O
PubChem CID	9854320

Physical properties
Physical form	Solid
LogP (XLogP3)	5.5
H-bond donors / acceptors	4 / 13
TPSA	206 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 7-O-Demethyl Rapamycin?

The CAS Registry Number of 7-O-Demethyl Rapamycin is 151519-50-5. It is also known as 7-O-Demethylsirolimus, 16-O-Demethylrapamycin, Rapamycin, 7-O-demethyl-.

What is the molecular formula and molecular weight of 7-O-Demethyl Rapamycin?

7-O-Demethyl Rapamycin has the molecular formula C50H77NO13 and a molecular weight of 900.1 g/mol.

What is 7-O-Demethyl Rapamycin used for?

7-O-Demethyl Rapamycin is supplied as a characterised reference material related to Rapamycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 7-O-Demethyl Rapamycin can I order?

We supply 7-O-Demethyl Rapamycin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 7-O-Demethyl Rapamycin?

Yes. Every lot of 7-O-Demethyl Rapamycin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 7-O-Demethyl Rapamycin be shipped internationally?

Yes. We export 7-O-Demethyl Rapamycin worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.