4,4-Dimethoxybutanenitrile

Name: 4,4-Dimethoxybutanenitrile
Brand: Vaqora Chemicals
SKU: VQ-051192

About 4,4-Dimethoxybutanenitrile

4,4-Dimethoxybutanenitrile (CAS 14618-78-1) is a process intermediate or related compound of Ribociclib offered by Vaqora Chemicals. With the molecular formula C6H11NO2, it has a molar mass of 129.16 g/mol. Common synonyms include 4,4-Dimethoxybutyronitrile and Butanenitrile, 4,4-dimethoxy-.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Ribociclib, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4,4-Dimethoxybutanenitrile is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Ribociclib

View every impurity, metabolite and intermediate we list for Ribociclib.

Ribociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	4,4-Dimethoxybutanenitrile
Catalogue No.	VQ-051192
CAS Number	14618-78-1
IUPAC name	4,4-dimethoxybutanenitrile
Molecular formula	C₆H₁₁NO₂
Molecular weight	129.16 g/mol
Exact mass	129.079
InChIKey	XJHNCGVHPLDMRK-UHFFFAOYSA-N
SMILES	COC(CCC#N)OC
PubChem CID	84558

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	0 / 3
TPSA	42.3 Å²
Synonyms	4,4-Dimethoxybutyronitrile, Butanenitrile, 4,4-dimethoxy-, Cyanopropionaldehyde dimethyl acetal, 3-Cyanopropionaldehyde dimethyl acetal, 3-Cyano propionaldehyde dimethyl acetal, .beta.-Cyanopropionaldehyde dimethylacetal, 4,4'-Dimethoxybutyronitrile, .beta.-Cyanopropional, 4-dimeth-oxybutyronitrile, Butanenitril, 4,-dimethyloxy-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,4-Dimethoxybutanenitrile?

The CAS Registry Number of 4,4-Dimethoxybutanenitrile is 14618-78-1. It is also known as 4,4-Dimethoxybutyronitrile, Butanenitrile, 4,4-dimethoxy-, Cyanopropionaldehyde dimethyl acetal.

What is the molecular formula and molecular weight of 4,4-Dimethoxybutanenitrile?

4,4-Dimethoxybutanenitrile has the molecular formula C6H11NO2 and a molecular weight of 129.16 g/mol. Its IUPAC name is 4,4-dimethoxybutanenitrile.

What is 4,4-Dimethoxybutanenitrile used for?

4,4-Dimethoxybutanenitrile is supplied as a characterised reference material related to Ribociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,4-Dimethoxybutanenitrile can I order?

We supply 4,4-Dimethoxybutanenitrile, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,4-Dimethoxybutanenitrile?

Yes. Every lot of 4,4-Dimethoxybutanenitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,4-Dimethoxybutanenitrile be shipped internationally?

Yes. 4,4-Dimethoxybutanenitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.