![1-(6-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide chemical structure](/media/structures/CATKDONZXJDZBW-UHFFFAOYSA-N.svg)
1-(6-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide
- CAS
- 2470164-21-5
- Formula
- C23H30N8O2
- MW
- 450.5 g/mol
VQ-041892
Impurity reference standards
Ribociclib impurities & reference standards
Characterised Ribociclib impurities, degradation products and related compounds for analytical method development, validation, QC release and regulatory filings.
51reference materials
2nitrosamine impurities
2isotope-labelled
COAHPLC · NMR · MS on request
Parent API: Ribociclib WS
1211441-98-3 · C23H30N8O
![2-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-Oxide chemical structure](/media/structures/ZDUURROEKWAQFW-QOMWVZHYSA-N.svg)
2-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-Oxide
- CAS
- 2069953-39-3
- Formula
- C23H30N8O2
- MW
- 450.5 g/mol
VQ-033521
![2-Amino-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide chemical structure](/media/structures/ZSEKPRGGCJNABQ-UHFFFAOYSA-N.svg)
2-Amino-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
- CAS
- 1331847-17-6
- Formula
- C14H19N5O
- MW
- 273.33 g/mol
VQ-027794
![2-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-d]Pyrimidine-6-Carbaldehyde chemical structure](/media/structures/SOXVKQLLJZHYTL-UHFFFAOYSA-N.svg)
2-Chloro-7-Cyclopentyl-7H-Pyrrolo[2,3-d]Pyrimidine-6-Carbaldehyde
- CAS
- 1211443-55-8
- Formula
- C12H12ClN3O
- MW
- 249.69 g/mol
VQ-032738
![2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic Acid chemical structure](/media/structures/LXCZVGKSFJMLRO-UHFFFAOYSA-N.svg)
2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic Acid
- CAS
- 1211443-58-1
- Formula
- C12H12ClN3O2
- MW
- 265.69 g/mol
VQ-027793
![2-Chloro-7-cyclopentyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide chemical structure](/media/structures/JATZKXQRAAGTGK-UHFFFAOYSA-N.svg)
2-Chloro-7-cyclopentyl-N-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
- CAS
- 1211444-14-2
- Formula
- C13H15ClN4O
- MW
- 278.74 g/mol
VQ-033525
![2,5-Dichloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide chemical structure](/media/structures/NGNDLDIPPYYJCK-UHFFFAOYSA-N.svg)
2,5-Dichloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
- CAS
- 2577288-43-6
- Formula
- C14H16Cl2N4O
- MW
- 327.2 g/mol
VQ-041893
3-(2-Chloro-4-(cyclopentylamino)pyrimidin-5-yl)prop-2-yn-1-ol
- CAS
- 1374639-76-5
- Formula
- C12H14ClN3O
- MW
- 251.71 g/mol
VQ-041891
5-Bromo-2-chloro-N-cyclopentylpyrimidin-4-amine
- CAS
- 733039-20-8
- Formula
- C9H11BrClN3
- MW
- 276.56 g/mol
VQ-033030
5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amine
- CAS
- 1823404-28-9
- Formula
- C9H11BrClN3
- MW
- 276.56 g/mol
VQ-023632
![7-Cyclopentyl-2-((3,6-dihydroxy-5-(piperazin-1-yl)pyridin-2-yl)amino)-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide](/media/pack/7-cyclopentyl-2-36-dihydroxy-5-piperazin-1-ylpyridin-2-ylamino-nn-dimethyl-7h-pyrrolo23.svg?v=3)
7-Cyclopentyl-2-((3,6-dihydroxy-5-(piperazin-1-yl)pyridin-2-yl)amino)-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
- CAS
- 3027550-94-0
- Formula
- C23H30N8O3
- MW
- 466.54 g/mol
VQ-044955
![7-Cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic Acid chemical structure](/media/structures/KKEUCZGFPZXMLO-UHFFFAOYSA-N.svg)
7-Cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic Acid
- CAS
- 2762182-61-4
- Formula
- C21H25N7O2
- MW
- 407.5 g/mol
VQ-033523
![7-Cyclopentyl-N-(hydroxymethyl)-N-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide chemical structure](/media/structures/IYVSETJXVPKRIT-UHFFFAOYSA-N.svg)
7-Cyclopentyl-N-(hydroxymethyl)-N-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
- CAS
- 2460734-07-8
- Formula
- C23H30N8O2
- MW
- 450.5 g/mol
VQ-033524
![7-Cyclopentyl-N,N-dimethyl-2-((5-(4-tritylpiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide chemical structure](/media/structures/IKSAVSJAJRREKD-UHFFFAOYSA-N.svg)
7-Cyclopentyl-N,N-dimethyl-2-((5-(4-tritylpiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
- CAS
- 2524428-16-6
- Formula
- C42H44N8O
- MW
- 676.9 g/mol
VQ-027796
Ribociclib Succinate Piperazine amide impurity
- CAS
- 3056250-51-9
- Formula
- C18H26N6O
- MW
- 342.45 g/mol
VQ-033529
![tert-Butyl 4-(6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate chemical structure](/media/structures/ZCVCEBXWRPIXKX-UHFFFAOYSA-N.svg)
tert-Butyl 4-(6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
- CAS
- 1374639-78-7
- Formula
- C28H38N8O3
- MW
- 534.7 g/mol
VQ-023631
FAQs — Ribociclib impurities
Which Ribociclib impurities do you supply?
We list 51 Ribociclib-related reference materials, including process impurities, degradation products, nitrosamine impurities, stable-isotope-labelled standards and related compounds. Each is supplied with a COA, and characterisation data (HPLC, 1H-NMR, MS, IR) can be provided on request.
What are Ribociclib impurity standards used for?
They are used for analytical method development and validation, impurity identification and quantification, forced-degradation and stability studies, and to support ANDA, DMF and other regulatory submissions under ICH Q3A/Q3B (and ICH M7 for mutagenic impurities).
Can you synthesise a Ribociclib impurity that is not listed?
Yes. Our custom synthesis service can prepare and characterise unlisted impurities, metabolites and labelled analogues from milligram to gram scale. Share the structure or name and required quantity for a quotation.
Request Ribociclib impurity standards
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