(4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymeth… 95058-77-8

Name: (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one
Brand: Vaqora Chemicals
SKU: VQ-030965

About (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one

(4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one (CAS 95058-77-8) is a metabolite or degradation product of Gemcitabine offered by Vaqora Chemicals. Its molecular formula is C5H6F2O4 and its molecular weight is 168.1 g/mol. The IUPAC name is (4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-one.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Gemcitabine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Gemcitabine

View every impurity, metabolite and intermediate we list for Gemcitabine.

Gemcitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	(4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one
Catalogue No.	VQ-030965
CAS Number	95058-77-8
IUPAC name	(4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-one
Molecular formula	C₅H₆F₂O₄
Molecular weight	168.1 g/mol
Exact mass	168.0234
Grade	Reference Standard
HSN code	38229090
InChIKey	FBXJTMLCLDWDQO-PWNYCUMCSA-N
SMILES	C([C@@H]1[C@H](C(C(=O)O1)(F)F)O)O
PubChem CID	10197873

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.1
H-bond donors / acceptors	2 / 6
TPSA	66.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one?

The CAS Registry Number of (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one is 95058-77-8. It is also known as 2-deoxy-2,2-difluoro-D-erythro-Pentonic acid gamma-Lactone, 2-deoxy-2,2-difluoro-D-erythro-pentofuranose-1-ulose, 2-deoxy-2,2-difluoro-D-ribonic acid-1,4-lactone.

What is the molecular formula and molecular weight of (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one?

(4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one has the molecular formula C5H6F2O4 and a molecular weight of 168.1 g/mol. Its IUPAC name is (4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-one.

What is (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one used for?

(4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one is supplied as a characterised reference material related to Gemcitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one can I order?

We supply (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one?

Yes. Every lot of (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one be shipped internationally?

Yes. We export (4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.