(4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahy… 861445-88-7

Name: (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol
Brand: Vaqora Chemicals
SKU: VQ-030966

About (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol

(4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol (CAS 861445-88-7) is a metabolite or degradation product of Gemcitabine offered by Vaqora Chemicals. The compound has the formula C5H8F2O4, corresponding to a molecular weight of 170.11 g/mol. The IUPAC name is (4R,5R)-3,3-difluoro-5-(hydroxymethyl)oxolane-2,4-diol. It is also known as 2-Deoxy-2,2-difluoro-D-erythro-pentofuranose or 2-deoxy-2,2-difluoro-d-ribofuranose.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Gemcitabine, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Gemcitabine

View every impurity, metabolite and intermediate we list for Gemcitabine.

Gemcitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	(4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol
Catalogue No.	VQ-030966
CAS Number	861445-88-7
IUPAC name	(4R,5R)-3,3-difluoro-5-(hydroxymethyl)oxolane-2,4-diol
Molecular formula	C₅H₈F₂O₄
Molecular weight	170.11 g/mol
Exact mass	170.0391
Grade	Reference Standard
HSN code	38229090
InChIKey	LDHXMQXUOUZOLF-HERZVMAMSA-N
SMILES	C([C@@H]1[C@H](C(C(O1)O)(F)F)O)O
PubChem CID	14057748

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.7
H-bond donors / acceptors	3 / 6
TPSA	69.9 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol?

The CAS Registry Number of (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol is 861445-88-7. It is also known as 2-Deoxy-2,2-difluoro-D-erythro-pentofuranose, 2-deoxy-2,2-difluoro-d-ribofuranose.

What is the molecular formula and molecular weight of (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol?

(4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol has the molecular formula C5H8F2O4 and a molecular weight of 170.11 g/mol. Its IUPAC name is (4R,5R)-3,3-difluoro-5-(hydroxymethyl)oxolane-2,4-diol.

What is (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol used for?

(4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol is supplied as a characterised reference material related to Gemcitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol can I order?

We supply (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol?

Yes. Every lot of (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol be shipped internationally?

Yes. We export (4R,5R)-3,3-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2,4-diol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.