(5-Chloropyrazin-2-yl)methanamine

Name: (5-Chloropyrazin-2-yl)methanamine
Brand: Vaqora Chemicals
SKU: VQ-024120

About (5-Chloropyrazin-2-yl)methanamine

(5-Chloropyrazin-2-yl)methanamine (CAS 1060814-53-0) is an impurity of Acalabrutinib offered by Vaqora Chemicals. With the molecular formula C5H6ClN3, it has a molar mass of 143.57 g/mol. Common synonyms include 5-Chloropyrazine-2-methanamine and 5-Chloro-2-pyrazinemethanamine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Acalabrutinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (5-Chloropyrazin-2-yl)methanamine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Acalabrutinib

View every impurity, metabolite and intermediate we list for Acalabrutinib.

Acalabrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(5-Chloropyrazin-2-yl)methanamine
Catalogue No.	VQ-024120
CAS Number	1060814-53-0
IUPAC name	(5-chloropyrazin-2-yl)methanamine
Molecular formula	C₅H₆ClN₃
Molecular weight	143.57 g/mol
Exact mass	143.025
Grade	Reference Standard
HSN code	38229090
InChIKey	SYZWYECIPSWFJM-UHFFFAOYSA-N
SMILES	C1=C(N=CC(=N1)Cl)CN
PubChem CID	21714700

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	1 / 3
TPSA	51.8 Å²

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (5-Chloropyrazin-2-yl)methanamine?

The CAS Registry Number of (5-Chloropyrazin-2-yl)methanamine is 1060814-53-0. It is also known as 5-Chloropyrazine-2-methanamine, 5-Chloro-2-pyrazinemethanamine, 1-(5-Chloropyrazin-2-yl)methanamine.

What is the molecular formula and molecular weight of (5-Chloropyrazin-2-yl)methanamine?

(5-Chloropyrazin-2-yl)methanamine has the molecular formula C5H6ClN3 and a molecular weight of 143.57 g/mol. Its IUPAC name is (5-chloropyrazin-2-yl)methanamine.

What is (5-Chloropyrazin-2-yl)methanamine used for?

(5-Chloropyrazin-2-yl)methanamine is supplied as a characterised reference material related to Acalabrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (5-Chloropyrazin-2-yl)methanamine can I order?

We supply (5-Chloropyrazin-2-yl)methanamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (5-Chloropyrazin-2-yl)methanamine?

Yes. Every lot of (5-Chloropyrazin-2-yl)methanamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (5-Chloropyrazin-2-yl)methanamine be shipped internationally?

Yes. (5-Chloropyrazin-2-yl)methanamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.