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API ImpuritiesReference StandardAvailable on request

Acalabrutinib R Isomer Intermediate Impurity

Synonyms: Benzyl (R)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate · Benzyl 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate, (R)- · Phenylmethyl (2R)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylate

CAS No.2198380-46-8
FormulaC18H18BrN5O2
Mol. weight416.30
Catalogue No.VQ-021391
PurityReference Standard
HSN38229090

Acalabrutinib R Isomer Intermediate Impurity (CAS 2198380-46-8) – Acalabrutinib impurity standard. C18H18BrN5O2, MW 416.3. With COA, ships worldwide.

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25 mg
50 mg
100 mg
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16-section GHS SDS
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About Acalabrutinib R Isomer Intermediate Impurity

Acalabrutinib R Isomer Intermediate Impurity is an impurity of Acalabrutinib carrying the CAS registry number 2198380-46-8. Formula C18H18BrN5O2, molecular weight 416.3 g/mol. Systematically, it is named benzyl (2R)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Acalabrutinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Acalabrutinib R Isomer Intermediate Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Industries

Related to Acalabrutinib

View every impurity, metabolite and intermediate we list for Acalabrutinib.

Acalabrutinib impurities

Specifications & identifiers

Chemical identifiers
Product nameAcalabrutinib R Isomer Intermediate Impurity
Catalogue No.VQ-021391
CAS Number2198380-46-8
IUPAC namebenzyl (2R)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
Molecular formulaC18H18BrN5O2
Molecular weight416.3 g/mol
Exact mass415.0644
GradeReference Standard
HSN code38229090
InChIKeyDLXYYJDQLZHBNU-CYBMUJFWSA-N
SMILESC1C[C@@H](N(C1)C(=O)OCC2=CC=CC=C2)C3=NC(=C4N3C=CN=C4N)Br
PubChem CID134129376
Physical properties
Physical formSolid
LogP (XLogP3)3.2
H-bond donors / acceptors1 / 5
TPSA85.8 Ų

Documents

Frequently asked questions

What is the CAS number of Acalabrutinib R Isomer Intermediate Impurity?

The CAS Registry Number of Acalabrutinib R Isomer Intermediate Impurity is 2198380-46-8. It is also known as Benzyl (R)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate, Benzyl 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate, (R)-, Phenylmethyl (2R)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-1-pyrrolidinecarboxylate.

What is the molecular formula and molecular weight of Acalabrutinib R Isomer Intermediate Impurity?

Acalabrutinib R Isomer Intermediate Impurity has the molecular formula C18H18BrN5O2 and a molecular weight of 416.3 g/mol. Its IUPAC name is benzyl (2R)-2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate.

What is Acalabrutinib R Isomer Intermediate Impurity used for?

Acalabrutinib R Isomer Intermediate Impurity is supplied as a characterised reference material related to Acalabrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acalabrutinib R Isomer Intermediate Impurity can I order?

We supply Acalabrutinib R Isomer Intermediate Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acalabrutinib R Isomer Intermediate Impurity?

Yes. Every lot of Acalabrutinib R Isomer Intermediate Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acalabrutinib R Isomer Intermediate Impurity be shipped internationally?

Yes. We export Acalabrutinib R Isomer Intermediate Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.

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