5-Cyano-2-methylpyridine

Name: 5-Cyano-2-methylpyridine
Brand: Vaqora Chemicals
SKU: VQ-049890

About 5-Cyano-2-methylpyridine

Listed under CAS 3222-48-8, 5-Cyano-2-methylpyridine is a process intermediate or related compound of Nicotinamide available from Vaqora Chemicals. With the molecular formula C7H6N2, it has a molar mass of 118.14 g/mol. Its systematic (IUPAC) name is 6-methylpyridine-3-carbonitrile. Alternative names: 5-Cyano-2-picoline and 6-Methylnicotinonitrile.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Nicotinamide, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 5-Cyano-2-methylpyridine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Nicotinamide

View every impurity, metabolite and intermediate we list for Nicotinamide.

Nicotinamide impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Cyano-2-methylpyridine
Catalogue No.	VQ-049890
CAS Number	3222-48-8
IUPAC name	6-methylpyridine-3-carbonitrile
Molecular formula	C₇H₆N₂
Molecular weight	118.14 g/mol
Exact mass	118.0531
HSN code	2933
InChIKey	PBLOYQAQGYUPCM-UHFFFAOYSA-N
SMILES	CC1=NC=C(C=C1)C#N
PubChem CID	281995

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	0 / 2
TPSA	36.7 Å²
Synonyms	5-Cyano-2-picoline, 6-Methylnicotinonitrile, 6-Methyl-nicotinonitrile, 6-Methyl-3-pyridinecarbonitrile, 2-methyl-5-cyanopyridine, 6-Methylnicotinonitrile #

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P316, P301 + P317, P302 + P352, P305 + P351 + P338, P305 + P354 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Cyano-2-methylpyridine?

The CAS Registry Number of 5-Cyano-2-methylpyridine is 3222-48-8. It is also known as 5-Cyano-2-picoline, 6-Methylnicotinonitrile, 6-Methyl-nicotinonitrile.

What is the molecular formula and molecular weight of 5-Cyano-2-methylpyridine?

5-Cyano-2-methylpyridine has the molecular formula C7H6N2 and a molecular weight of 118.14 g/mol. Its IUPAC name is 6-methylpyridine-3-carbonitrile.

What is 5-Cyano-2-methylpyridine used for?

5-Cyano-2-methylpyridine is supplied as a characterised reference material related to Nicotinamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Cyano-2-methylpyridine can I order?

We supply 5-Cyano-2-methylpyridine, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Cyano-2-methylpyridine?

Yes. Every lot of 5-Cyano-2-methylpyridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Cyano-2-methylpyridine be shipped internationally?

Yes. 5-Cyano-2-methylpyridine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.