5-Hydroxy-4-methyl-2(5H)-furanone

Name: 5-Hydroxy-4-methyl-2(5H)-furanone
Brand: Vaqora Chemicals
SKU: VQ-039838

About 5-Hydroxy-4-methyl-2(5H)-furanone

5-Hydroxy-4-methyl-2(5H)-furanone (CAS 40834-42-2) is a metabolite or degradation product of Isotretinoin offered by Vaqora Chemicals. The compound has the formula C5H6O3, corresponding to a molecular weight of 114.1 g/mol. Its systematic (IUPAC) name is 2-hydroxy-3-methyl-2H-furan-5-one. Common synonyms include 5-hydroxy-4-methyl-2,5-dihydrofuran-2-one and 2(5H)-Furanone, 5-hydroxy-4-methyl-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Isotretinoin, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5-Hydroxy-4-methyl-2(5H)-furanone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Isotretinoin

View every impurity, metabolite and intermediate we list for Isotretinoin.

Isotretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Hydroxy-4-methyl-2(5H)-furanone
Catalogue No.	VQ-039838
CAS Number	40834-42-2
IUPAC name	2-hydroxy-3-methyl-2H-furan-5-one
Molecular formula	C₅H₆O₃
Molecular weight	114.1 g/mol
Exact mass	114.0317
Grade	Reference Standard
HSN code	38229090
InChIKey	XRNPHZPFAWLRNJ-UHFFFAOYSA-N
SMILES	CC1=CC(=O)OC1O
PubChem CID	115301

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	1 / 3
TPSA	46.5 Å²
Synonyms	5-hydroxy-4-methyl-2,5-dihydrofuran-2-one, 2(5H)-Furanone, 5-hydroxy-4-methyl-, 4-Methyl-5-hydroxy-2(5H)-furanone, 5-hydroxy-4-methylfuran-2(5H)-one, 5-Hydroxy-4-methyl-5H-furan-2-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Hydroxy-4-methyl-2(5H)-furanone?

The CAS Registry Number of 5-Hydroxy-4-methyl-2(5H)-furanone is 40834-42-2. It is also known as 5-hydroxy-4-methyl-2,5-dihydrofuran-2-one, 2(5H)-Furanone, 5-hydroxy-4-methyl-, 4-Methyl-5-hydroxy-2(5H)-furanone.

What is the molecular formula and molecular weight of 5-Hydroxy-4-methyl-2(5H)-furanone?

5-Hydroxy-4-methyl-2(5H)-furanone has the molecular formula C5H6O3 and a molecular weight of 114.1 g/mol. Its IUPAC name is 2-hydroxy-3-methyl-2H-furan-5-one.

What is 5-Hydroxy-4-methyl-2(5H)-furanone used for?

5-Hydroxy-4-methyl-2(5H)-furanone is supplied as a characterised reference material related to Isotretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Hydroxy-4-methyl-2(5H)-furanone can I order?

We supply 5-Hydroxy-4-methyl-2(5H)-furanone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Hydroxy-4-methyl-2(5H)-furanone?

Yes. Every lot of 5-Hydroxy-4-methyl-2(5H)-furanone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Hydroxy-4-methyl-2(5H)-furanone be shipped internationally?

Yes. 5-Hydroxy-4-methyl-2(5H)-furanone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.