6-Chloro-2-Picolinic Acid Methyl Ester

Name: 6-Chloro-2-Picolinic Acid Methyl Ester
Brand: Vaqora Chemicals
SKU: VQ-044559

About 6-Chloro-2-Picolinic Acid Methyl Ester

6-Chloro-2-Picolinic Acid Methyl Ester is an impurity of Sorafenib carrying the CAS registry number 6636-55-1. The compound has the formula C7H6ClNO2, corresponding to a molecular weight of 171.58 g/mol. Systematically, it is named methyl 6-chloropyridine-2-carboxylate. Common synonyms include Methyl 6-chloropicolinate and Methyl 6-chloro-2-pyridinecarboxylate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Sorafenib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 6-Chloro-2-Picolinic Acid Methyl Ester in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sorafenib

View every impurity, metabolite and intermediate we list for Sorafenib.

Sorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Chloro-2-Picolinic Acid Methyl Ester
Catalogue No.	VQ-044559
CAS Number	6636-55-1
IUPAC name	methyl 6-chloropyridine-2-carboxylate
Molecular formula	C₇H₆ClNO₂
Molecular weight	171.58 g/mol
Exact mass	171.0087
Grade	Reference Standard
HSN code	38229090
InChIKey	TWUXBVMXSBEKHA-UHFFFAOYSA-N
SMILES	COC(=O)C1=NC(=CC=C1)Cl
PubChem CID	242723

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	0 / 3
TPSA	39.2 Å²
Synonyms	Methyl 6-chloropicolinate, 6-ethenyl-3,6-dimethyl-7-(prop-1-en-2-yl)-hexahydro-1-benzofuran-2-one, Methyl 6-chloro-2-pyridinecarboxylate, 2-Pyridinecarboxylic acid, 6-chloro-, methyl ester, 6-Chloropicolinic Acid Methyl Ester, Methyl 6-chloro-pyridine-2-carboxylate, Picolinic acid, 6-chloro-, methyl ester, 6-chloro-pyridine-2-carboxylic acid methyl ester, 2-Pyridinecarboxylic acid, 6-chloro-, me, 6-chloro-2-pyridinecarboxylic acid, methyl ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Chloro-2-Picolinic Acid Methyl Ester?

The CAS Registry Number of 6-Chloro-2-Picolinic Acid Methyl Ester is 6636-55-1. It is also known as Methyl 6-chloropicolinate, 6-ethenyl-3,6-dimethyl-7-(prop-1-en-2-yl)-hexahydro-1-benzofuran-2-one, Methyl 6-chloro-2-pyridinecarboxylate.

What is the molecular formula and molecular weight of 6-Chloro-2-Picolinic Acid Methyl Ester?

6-Chloro-2-Picolinic Acid Methyl Ester has the molecular formula C7H6ClNO2 and a molecular weight of 171.58 g/mol. Its IUPAC name is methyl 6-chloropyridine-2-carboxylate.

What is 6-Chloro-2-Picolinic Acid Methyl Ester used for?

6-Chloro-2-Picolinic Acid Methyl Ester is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Chloro-2-Picolinic Acid Methyl Ester can I order?

We supply 6-Chloro-2-Picolinic Acid Methyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Chloro-2-Picolinic Acid Methyl Ester?

Yes. Every lot of 6-Chloro-2-Picolinic Acid Methyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Chloro-2-Picolinic Acid Methyl Ester be shipped internationally?

Yes. 6-Chloro-2-Picolinic Acid Methyl Ester is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.