6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimid… 1548397-10-9

Name: 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone
Brand: Vaqora Chemicals
SKU: VQ-028374

About 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone

Listed under CAS 1548397-10-9, 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone is an impurity of Ticagrelor available from Vaqora Chemicals. The compound has the formula C7H8ClN3O3S, corresponding to a molecular weight of 249.68 g/mol. Its systematic (IUPAC) name is 4-chloro-5-nitro-2-propylsulfanyl-1H-pyrimidin-6-one. Common synonyms include 6-Chloro-5-nitro-2-(propylthio)pyrimidin-4-ol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Ticagrelor to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ticagrelor

View every impurity, metabolite and intermediate we list for Ticagrelor.

Ticagrelor impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone
Catalogue No.	VQ-028374
CAS Number	1548397-10-9
IUPAC name	4-chloro-5-nitro-2-propylsulfanyl-1H-pyrimidin-6-one
Molecular formula	C₇H₈ClN₃O₃S
Molecular weight	249.68 g/mol
Exact mass	248.9975
Grade	Reference Standard
HSN code	38229090
InChIKey	GXBABSVBIPUOLI-UHFFFAOYSA-N
SMILES	CCCSC1=NC(=C(C(=O)N1)[N+](=O)[O-])Cl
PubChem CID	136236969

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 5
TPSA	113 Å²
Synonyms	6-Chloro-5-nitro-2-(propylthio)pyrimidin-4(1H)-one, 6-chloro-5-nitro-2-(propylthio)pyrimidin-4(3H)-one, 6-chloro-5-nitro-2-(propylsulfanyl)pyrimidin-4-ol, 6-Chloro-5-nitro-2-(propylthio)pyrimidin-4-ol, 6-chloro-5-nitro-2-propylsulfanyl-1H-pyrimidin-4-one, 4(1H)-Pyrimidinone, 6-chloro-5-nitro-2-(propylthio)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone?

The CAS Registry Number of 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone is 1548397-10-9. It is also known as 6-Chloro-5-nitro-2-(propylthio)pyrimidin-4(1H)-one, 6-chloro-5-nitro-2-(propylthio)pyrimidin-4(3H)-one, 6-chloro-5-nitro-2-(propylsulfanyl)pyrimidin-4-ol.

What is the molecular formula and molecular weight of 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone?

6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone has the molecular formula C7H8ClN3O3S and a molecular weight of 249.68 g/mol. Its IUPAC name is 4-chloro-5-nitro-2-propylsulfanyl-1H-pyrimidin-6-one.

What is 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone used for?

6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone is supplied as a characterised reference material related to Ticagrelor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone can I order?

We supply 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone?

Yes. Every lot of 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone be shipped internationally?

Yes. 6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.