6-Keto Estrone

Name: 6-Keto Estrone
Brand: Vaqora Chemicals
SKU: VQ-025648

About 6-Keto Estrone

6-Keto Estrone (CAS 1476-34-2) is an impurity of Estrone offered by Vaqora Chemicals. With the molecular formula C18H20O3, it has a molar mass of 284.3 g/mol. The IUPAC name is (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-6,17-dione. Common synonyms include 3-Hydroxyestra-1,3,5(10)-triene-6,17-dione and Estra-1,3,5(10)-triene-6,17-dione, 3-hydroxy-.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Estrone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 6-Keto Estrone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Estrone

View every impurity, metabolite and intermediate we list for Estrone.

Estrone impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Keto Estrone
Catalogue No.	VQ-025648
CAS Number	1476-34-2
IUPAC name	(8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-6,17-dione
Molecular formula	C₁₈H₂₀O₃
Molecular weight	284.3 g/mol
Exact mass	284.1412
Grade	Reference Standard
HSN code	38229090
InChIKey	JOVYPIGRPWIXHQ-ONUSSAAZSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC(=O)C4=C3C=CC(=C4)O
PubChem CID	12985714

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 3
TPSA	54.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Keto Estrone?

The CAS Registry Number of 6-Keto Estrone is 1476-34-2. It is also known as 3-Hydroxyestra-1,3,5(10)-triene-6,17-dione, Estra-1,3,5(10)-triene-6,17-dione, 3-hydroxy-, 6-Oxoestrone.

What is the molecular formula and molecular weight of 6-Keto Estrone?

6-Keto Estrone has the molecular formula C18H20O3 and a molecular weight of 284.3 g/mol. Its IUPAC name is (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-6,17-dione.

What is 6-Keto Estrone used for?

6-Keto Estrone is supplied as a characterised reference material related to Estrone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Keto Estrone can I order?

We supply 6-Keto Estrone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Keto Estrone?

Yes. Every lot of 6-Keto Estrone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Keto Estrone be shipped internationally?

Yes. We export 6-Keto Estrone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.