Estrone-3-Methyl Ether

Name: Estrone-3-Methyl Ether
Brand: Vaqora Chemicals
SKU: VQ-025640

About Estrone-3-Methyl Ether

Vaqora Chemicals supplies Estrone-3-Methyl Ether, an impurity of Estrone registered under CAS number 1624-62-0. The compound has the formula C19H24O2, corresponding to a molecular weight of 284.4 g/mol. Its systematic (IUPAC) name is (8R,9S,13S,14S)-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one. Alternative names: Oestrone methyl ether and Estrone methyl ether.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Estrone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Estrone-3-Methyl Ether in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Estrone

View every impurity, metabolite and intermediate we list for Estrone.

Estrone impurities

Specifications & identifiers

Chemical identifiers
Product name	Estrone-3-Methyl Ether
Catalogue No.	VQ-025640
CAS Number	1624-62-0
IUPAC name	(8R,9S,13S,14S)-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
Molecular formula	C₁₉H₂₄O₂
Molecular weight	284.4 g/mol
Exact mass	284.1776
Grade	Reference Standard
HSN code	38229090
InChIKey	BCWWDWHFBMPLFQ-VXNCWWDNSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)OC
PubChem CID	92895

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	0 / 2
TPSA	26.3 Å²
Synonyms	Oestrone methyl ether, Estrone methyl ether, 3-o-methyl estrone, Estra-1,3,5(10)-trien-17-one, 3-methoxy-, 3-Methoxyestrone, 3-Methoxyestra-1,3,5(10)-trien-17-one, DL-Estrone methyl ether, (+/-)-O-Methylestrone, Estrone methyl ether, DL-, Estrone methyl ether, (+/-)-, 3-Methoxyoestra-1,3,5(10)-trien-17-one

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Estrone-3-Methyl Ether?

The CAS Registry Number of Estrone-3-Methyl Ether is 1624-62-0. It is also known as Oestrone methyl ether, Estrone methyl ether, 3-o-methyl estrone.

What is the molecular formula and molecular weight of Estrone-3-Methyl Ether?

Estrone-3-Methyl Ether has the molecular formula C19H24O2 and a molecular weight of 284.4 g/mol. Its IUPAC name is (8R,9S,13S,14S)-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one.

What is Estrone-3-Methyl Ether used for?

Estrone-3-Methyl Ether is supplied as a characterised reference material related to Estrone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Estrone-3-Methyl Ether can I order?

We supply Estrone-3-Methyl Ether in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Estrone-3-Methyl Ether?

Yes. Every lot of Estrone-3-Methyl Ether is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Estrone-3-Methyl Ether be shipped internationally?

Yes. Estrone-3-Methyl Ether is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.