6a-Hydroxy Paclitaxel

Name: 6a-Hydroxy Paclitaxel
Brand: Vaqora Chemicals
SKU: VQ-033026

About 6a-Hydroxy Paclitaxel

Vaqora Chemicals supplies 6a-Hydroxy Paclitaxel, a metabolite or degradation product of Paclitaxel registered under CAS number 153212-75-0. Its molecular formula is C47H51NO15 and its molecular weight is 869.9 g/mol. It is also known as 6alpha-Hydroxy Paclitaxel or 6-Hydroxytaxol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Paclitaxel, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 6a-Hydroxy Paclitaxel in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Paclitaxel

View every impurity, metabolite and intermediate we list for Paclitaxel.

Paclitaxel impurities

Specifications & identifiers

Chemical identifiers
Product name	6a-Hydroxy Paclitaxel
Catalogue No.	VQ-033026
CAS Number	153212-75-0
IUPAC name	[(1S,2S,3R,4S,7R,8S,9R,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,8,9-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Molecular formula	C₄₇H₅₁NO₁₅
Molecular weight	869.9 g/mol
Exact mass	869.3259
Grade	Reference Standard
HSN code	38229090
InChIKey	NDCWHEDPSFRTDA-FJMWQILYSA-N
SMILES	CC1=C2[C@H](C(=O)[C@]3([C@H]([C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C4=CC=CC=C4)NC(=O)C5=CC=CC=C5)O)O)OC(=O)C6=CC=CC=C6)[C@@]7(CO[C@@H]7[C@H]([C@@H]3O)O)OC(=O)C)C)OC(=O)C
PubChem CID	10056458

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	5 / 15
TPSA	242 Å²
Synonyms	6alpha-Hydroxy Paclitaxel, 6-Hydroxytaxol, 6-hydroxy-taxol, 6alpha-hydroxypaclitaxel, 6-Hydroxypaclitaxel, 6alpha-Hydroxytaxol, 6.alpha.-hydroxy Paclitaxel, 6a-Hydroxy taxol, 6, _-hydroxy Paclitaxel, US9333197, 6alpha-Hydroxypaclitaxel

Safety & hazard information (GHS)

Corrosive

Health hazard

Signal word: Danger

Hazard statements

H318Causes serious eye damage
H340May cause genetic defects
H360May damage fertility or the unborn child

Precautionary statements: P203, P264 + P265, P280, P305 + P354 + P338, P317, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6a-Hydroxy Paclitaxel?

The CAS Registry Number of 6a-Hydroxy Paclitaxel is 153212-75-0. It is also known as 6alpha-Hydroxy Paclitaxel, 6-Hydroxytaxol, 6-hydroxy-taxol.

What is the molecular formula and molecular weight of 6a-Hydroxy Paclitaxel?

6a-Hydroxy Paclitaxel has the molecular formula C47H51NO15 and a molecular weight of 869.9 g/mol.

What is 6a-Hydroxy Paclitaxel used for?

6a-Hydroxy Paclitaxel is supplied as a characterised reference material related to Paclitaxel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6a-Hydroxy Paclitaxel can I order?

We supply 6a-Hydroxy Paclitaxel in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6a-Hydroxy Paclitaxel?

Yes. Every lot of 6a-Hydroxy Paclitaxel is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6a-Hydroxy Paclitaxel be shipped internationally?

Yes. 6a-Hydroxy Paclitaxel is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.