N-DesBoc Docetaxel

Name: N-DesBoc Docetaxel
Brand: Vaqora Chemicals
SKU: VQ-036764

About N-DesBoc Docetaxel

Vaqora Chemicals supplies N-DesBoc Docetaxel, an impurity of Paclitaxel registered under CAS number 133524-69-3. Formula C38H45NO12, molecular weight 707.8 g/mol. Alternative names: N-Deboc-docetaxel and 10-Deacetyl-3'-debenzoylpaclitaxel.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Paclitaxel to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Paclitaxel

View every impurity, metabolite and intermediate we list for Paclitaxel.

Paclitaxel impurities

Specifications & identifiers

Chemical identifiers
Product name	N-DesBoc Docetaxel
Catalogue No.	VQ-036764
CAS Number	133524-69-3
IUPAC name	[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-15-[(2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl]oxy-1,9,12-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Molecular formula	C₃₈H₄₅NO₁₂
Molecular weight	707.8 g/mol
Exact mass	707.2942
Grade	Reference Standard
HSN code	38229090
InChIKey	QCOGLDHTESFSPY-BFLUDPMCSA-N
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)N)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
PubChem CID	11422650

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 13
TPSA	212 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-DesBoc Docetaxel?

The CAS Registry Number of N-DesBoc Docetaxel is 133524-69-3. It is also known as N-Deboc-docetaxel, 10-Deacetyl-3'-debenzoylpaclitaxel, 10-Deacetylbaccatin III 13-[BETA(S)-AMINO-ALPHA(R)-HYDROXYPHENYLPROPIONATE].

What is the molecular formula and molecular weight of N-DesBoc Docetaxel?

N-DesBoc Docetaxel has the molecular formula C38H45NO12 and a molecular weight of 707.8 g/mol.

What is N-DesBoc Docetaxel used for?

N-DesBoc Docetaxel is supplied as a characterised reference material related to Paclitaxel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-DesBoc Docetaxel can I order?

We supply N-DesBoc Docetaxel in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-DesBoc Docetaxel?

Yes. Every lot of N-DesBoc Docetaxel is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-DesBoc Docetaxel be shipped internationally?

Yes. N-DesBoc Docetaxel is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.