6beta-Hydroxy 17beta-Estradiol

Name: 6beta-Hydroxy 17beta-Estradiol
Brand: Vaqora Chemicals
SKU: VQ-022562

About 6beta-Hydroxy 17beta-Estradiol

Listed under CAS 3583-03-7, 6beta-Hydroxy 17beta-Estradiol is a metabolite or degradation product of Estradiol available from Vaqora Chemicals. The compound has the formula C18H24O3, corresponding to a molecular weight of 288.4 g/mol. The IUPAC name is (6R,8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,6,17-triol. Common synonyms include 6Beta-Hydroxyestradiol and 6-Beta Hydroxyestradiol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Estradiol, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Estradiol

View every impurity, metabolite and intermediate we list for Estradiol.

Estradiol impurities

Specifications & identifiers

Chemical identifiers
Product name	6beta-Hydroxy 17beta-Estradiol
Catalogue No.	VQ-022562
CAS Number	3583-03-7
IUPAC name	(6R,8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,6,17-triol
Molecular formula	C₁₈H₂₄O₃
Molecular weight	288.4 g/mol
Exact mass	288.1725
Grade	Reference Standard
HSN code	38229090
InChIKey	QZZRQURPSRWTLG-UXCAXZQLSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)C[C@H](C4=C3C=CC(=C4)O)O
PubChem CID	440168

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	3 / 3
TPSA	60.7 Å²
Synonyms	6Beta-Hydroxyestradiol, 6-Beta Hydroxyestradiol, 6β-Hydroxy 17β-Estradiol, 6beta-Hydroxyestradiol-17beta, estra-1,3,5(10)-triene-3,6beta,17beta-triol, 6betaHydroxy estradiol, Estra-1,3,5(10)-triene-3,6,17-triol, (6beta,17beta)-, 6, A-Hydroxy 17, A-Estradiol, 6-beta-Hydroxy Estradiol, 6b-hydroxyestra-1,3,5(10)-triene-3,17b-diol

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P264, P270, P271, P284, P301 + P317, P304 + P340, P330, P342 + P316, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6beta-Hydroxy 17beta-Estradiol?

The CAS Registry Number of 6beta-Hydroxy 17beta-Estradiol is 3583-03-7. It is also known as 6Beta-Hydroxyestradiol, 6-Beta Hydroxyestradiol, 6β-Hydroxy 17β-Estradiol.

What is the molecular formula and molecular weight of 6beta-Hydroxy 17beta-Estradiol?

6beta-Hydroxy 17beta-Estradiol has the molecular formula C18H24O3 and a molecular weight of 288.4 g/mol. Its IUPAC name is (6R,8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,6,17-triol.

What is 6beta-Hydroxy 17beta-Estradiol used for?

6beta-Hydroxy 17beta-Estradiol is supplied as a characterised reference material related to Estradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6beta-Hydroxy 17beta-Estradiol can I order?

We supply 6beta-Hydroxy 17beta-Estradiol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6beta-Hydroxy 17beta-Estradiol?

Yes. Every lot of 6beta-Hydroxy 17beta-Estradiol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6beta-Hydroxy 17beta-Estradiol be shipped internationally?

Yes. 6beta-Hydroxy 17beta-Estradiol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.