Estradiol Hemihydrate EP Impurity C

Name: Estradiol Hemihydrate EP Impurity C
Brand: Vaqora Chemicals
SKU: VQ-022561

About Estradiol Hemihydrate EP Impurity C

Vaqora Chemicals supplies Estradiol Hemihydrate EP Impurity C, a pharmacopeial impurity of Estradiol registered under CAS number 6171-48-8. Formula C19H26O2, molecular weight 286.4 g/mol. The IUPAC name is (8R,9S,13S,14S,17S)-4,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol. Alternative names: 4-Methyl Estradiol and Estradiol Hemihydrate Impurity C.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Estradiol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Estradiol Hemihydrate EP Impurity C in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Estradiol

View every impurity, metabolite and intermediate we list for Estradiol.

Estradiol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Estradiol Hemihydrate EP Impurity C
Catalogue No.	VQ-022561
CAS Number	6171-48-8
IUPAC name	(8R,9S,13S,14S,17S)-4,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Molecular formula	C₁₉H₂₆O₂
Molecular weight	286.4 g/mol
Exact mass	286.1933
Grade	Reference Standard
HSN code	38229090
InChIKey	CSHOYPMKTGTOLM-SMYFESCOSA-N
SMILES	CC1=C(C=CC2=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C)O
PubChem CID	66437

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²
Synonyms	4-Methyl Estradiol, Estradiol Hemihydrate Impurity C, Estradiol Hemihydrate - Impurity C, 4-Methylestradiol, Estra-1,3,5(10)-triene-3,17-diol, 4-methyl-, (17beta)-, 4- Methyl Estradiol, (17beta)-4-Methylestra-1,3,5(10)-triene-3,17-diol, 4-Methylestra-1,3,5(10)-triene-3,17beta-diol (4-Methylestradiol), (17b)-4-Methylestra-1,3,5(10)-triene-3,17-diol, 8beta,9alpha-4,9-Cyclo-9,10-secoandrosta-1,3,5(10)-triene-1,17beta-diol

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H341Suspected of causing genetic defects

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Estradiol Hemihydrate EP Impurity C?

The CAS Registry Number of Estradiol Hemihydrate EP Impurity C is 6171-48-8. It is also known as 4-Methyl Estradiol, Estradiol Hemihydrate Impurity C, Estradiol Hemihydrate - Impurity C.

What is the molecular formula and molecular weight of Estradiol Hemihydrate EP Impurity C?

Estradiol Hemihydrate EP Impurity C has the molecular formula C19H26O2 and a molecular weight of 286.4 g/mol. Its IUPAC name is (8R,9S,13S,14S,17S)-4,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol.

What is Estradiol Hemihydrate EP Impurity C used for?

Estradiol Hemihydrate EP Impurity C is supplied as a characterised reference material related to Estradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Estradiol Hemihydrate EP Impurity C can I order?

We supply Estradiol Hemihydrate EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Estradiol Hemihydrate EP Impurity C?

Yes. Every lot of Estradiol Hemihydrate EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Estradiol Hemihydrate EP Impurity C be shipped internationally?

Yes. Estradiol Hemihydrate EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.