6beta-Hydroxy-7alpha-thiomethylspirolactone

Name: 6beta-Hydroxy-7alpha-thiomethylspirolactone
Brand: Vaqora Chemicals
SKU: VQ-042266

About 6beta-Hydroxy-7alpha-thiomethylspirolactone

Listed under CAS 42219-60-3, 6beta-Hydroxy-7alpha-thiomethylspirolactone is a metabolite or degradation product of Spironolactone available from Vaqora Chemicals. With the molecular formula C23H32O4S, it has a molar mass of 404.6 g/mol. Alternative names: 6-Hydroxy-7-thiomethylspirolactone and 6-OH-7-Sms.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Spironolactone, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 6beta-Hydroxy-7alpha-thiomethylspirolactone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Spironolactone

View every impurity, metabolite and intermediate we list for Spironolactone.

Spironolactone impurities

Specifications & identifiers

Chemical identifiers
Product name	6beta-Hydroxy-7alpha-thiomethylspirolactone
Catalogue No.	VQ-042266
CAS Number	42219-60-3
IUPAC name	(6S,7S,8R,9S,10R,13S,14S,17R)-6-hydroxy-10,13-dimethyl-7-methylsulfanylspiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione
Molecular formula	C₂₃H₃₂O₄S
Molecular weight	404.6 g/mol
Exact mass	404.2021
Grade	Reference Standard
HSN code	38229090
InChIKey	NWLBSWATTSRBOV-DFSNYPBXSA-N
SMILES	C[C@]12CCC(=O)C=C1[C@@H]([C@H]([C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]45CCC(=O)O5)C)SC)O
PubChem CID	40580543

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 5
TPSA	88.9 Å²
Synonyms	6beta-Hydroxy-7alpha-(thiomethyl)Spironolactone, 6-Hydroxy-7-thiomethylspirolactone, 6-OH-7-Sms, 6b-Hydroxy-7a-(thiomethyl) Spironolactone, 6b-Hydroxy-7a-(methylthio)spirolactone, 6beta-Hydroxy-7alpha-thiomethyl-spironolactone

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6beta-Hydroxy-7alpha-thiomethylspirolactone?

The CAS Registry Number of 6beta-Hydroxy-7alpha-thiomethylspirolactone is 42219-60-3. It is also known as 6beta-Hydroxy-7alpha-(thiomethyl)Spironolactone, 6-Hydroxy-7-thiomethylspirolactone, 6-OH-7-Sms.

What is the molecular formula and molecular weight of 6beta-Hydroxy-7alpha-thiomethylspirolactone?

6beta-Hydroxy-7alpha-thiomethylspirolactone has the molecular formula C23H32O4S and a molecular weight of 404.6 g/mol.

What is 6beta-Hydroxy-7alpha-thiomethylspirolactone used for?

6beta-Hydroxy-7alpha-thiomethylspirolactone is supplied as a characterised reference material related to Spironolactone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6beta-Hydroxy-7alpha-thiomethylspirolactone can I order?

We supply 6beta-Hydroxy-7alpha-thiomethylspirolactone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6beta-Hydroxy-7alpha-thiomethylspirolactone?

Yes. Every lot of 6beta-Hydroxy-7alpha-thiomethylspirolactone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6beta-Hydroxy-7alpha-thiomethylspirolactone be shipped internationally?

Yes. We export 6beta-Hydroxy-7alpha-thiomethylspirolactone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.