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Pharmacopeial Impurities (EP / USP / BP)Reference StandardAvailable on request

Spironolactone EP impurity A

Synonyms: Spironolactone - Impurity A · Spironolactone Related Compound B · 20,21-Dehydro Spironolactone · delta20-Spironolactone

CAS No.132458-33-4
FormulaC24H30O4S
Mol. weight414.60
Catalogue No.VQ-028118
PurityReference Standard
HSN38229090

Spironolactone EP impurity A (CAS 132458-33-4) – Spironolactone impurity standard. C24H30O4S, MW 414.6. Request a quote: COA, bulk packs and worldwide export.

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About Spironolactone EP impurity A

Spironolactone EP impurity A (CAS 132458-33-4) is a pharmacopeial impurity of Spironolactone offered by Vaqora Chemicals. Its molecular formula is C24H30O4S and its molecular weight is 414.6 g/mol. It is also known as Spironolactone - Impurity A or Spironolactone Related Compound B.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Spironolactone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Spironolactone EP impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

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Related to Spironolactone

View every impurity, metabolite and intermediate we list for Spironolactone.

Spironolactone impurities

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Specifications & identifiers

Chemical identifiers
Product nameSpironolactone EP impurity A
Catalogue No.VQ-028118
CAS Number132458-33-4
IUPAC nameS-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate
Molecular formulaC24H30O4S
Molecular weight414.6 g/mol
Exact mass414.1865
GradeReference Standard
HSN code38229090
InChIKeyKCWOLKZQDUPWRC-ZHYRCANASA-N
SMILESCC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)C=CC(=O)O5)C
PubChem CID14748917
Physical properties
Physical formSolid
LogP (XLogP3)3.7
H-bond donors / acceptors0 / 5
TPSA85.7 Ų
SynonymsSpironolactone - Impurity A, Spironolactone Related Compound B, 20,21-Dehydro Spironolactone, delta20-Spironolactone, (2R)-3,4-Dihydro-5H-spiro(androst-4,6-diene-17,2-furan)-3,5-dione., (2'R)-7alpha-(Acetylthio)-5'H-spiro(androst-4-ene-17,2'-furan)-3,5'-dione, S-((2R)-3,5-Dioxo-5H-spiro(androst-4-ene-17,2-furan)-7alpha-yl) ethanethioate

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Frequently asked questions

What is the CAS number of Spironolactone EP impurity A?

The CAS Registry Number of Spironolactone EP impurity A is 132458-33-4. It is also known as Spironolactone - Impurity A, Spironolactone Related Compound B, 20,21-Dehydro Spironolactone.

What is the molecular formula and molecular weight of Spironolactone EP impurity A?

Spironolactone EP impurity A has the molecular formula C24H30O4S and a molecular weight of 414.6 g/mol. Its IUPAC name is S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-furan]-7-yl] ethanethioate.

What is Spironolactone EP impurity A used for?

Spironolactone EP impurity A is supplied as a characterised reference material related to Spironolactone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Spironolactone EP impurity A can I order?

We supply Spironolactone EP impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Spironolactone EP impurity A?

Yes. Every lot of Spironolactone EP impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Spironolactone EP impurity A be shipped internationally?

Yes. We export Spironolactone EP impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.

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