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![8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine (CAS 125743-81-9) chemical structure](/media/structures/IJBTXWXMLWHVCI-UHFFFAOYSA-N.svg)
VAQORA8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine
CAS No.125743-81-9
FormulaC20H22ClFN2
Mol. weight344.90
Catalogue No.VQ-036629
PurityReference Standard
HSN38229090
8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine (CAS 125743-81-9) – Loratadine impurity standard.
Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
Enquire Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing
About 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine
8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine is an impurity of Loratadine carrying the CAS registry number 125743-81-9. Its molecular formula is C20H22ClFN2 and its molecular weight is 344.9 g/mol. Systematically, it is named 13-chloro-2-fluoro-2-(1-methylpiperidin-4-yl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene.
It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.
This Loratadine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine is dispatched with a Certificate of Analysis (COA) to destinations worldwide. SDS and detailed specification sheets can be requested with your quotation.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
Related to Loratadine
View every impurity, metabolite and intermediate we list for Loratadine.
Loratadine impuritiesSpecifications & identifiers
| Product name | 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine |
|---|---|
| Catalogue No. | VQ-036629 |
| CAS Number | 125743-81-9 |
| IUPAC name | 13-chloro-2-fluoro-2-(1-methylpiperidin-4-yl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene |
| Molecular formula | C20H22ClFN2 |
| Molecular weight | 344.9 g/mol |
| Exact mass | 344.1456 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | IJBTXWXMLWHVCI-UHFFFAOYSA-N |
| SMILES | CN1CCC(CC1)C2(C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)F |
| PubChem CID | 14621157 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 4.3 |
| H-bond donors / acceptors | 0 / 3 |
| TPSA | 16.1 Ų |
Documents
Frequently asked questions
What is the CAS number of 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine?
The CAS Registry Number of 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine is 125743-81-9.
What is the molecular formula and molecular weight of 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine?
8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine has the molecular formula C20H22ClFN2 and a molecular weight of 344.9 g/mol. Its IUPAC name is 13-chloro-2-fluoro-2-(1-methylpiperidin-4-yl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene.
What is 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine used for?
8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine is supplied as a characterised reference material related to Loratadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine can I order?
We supply 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine?
Yes. Every lot of 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine be shipped internationally?
Yes. We export 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about 8-Chloro-11-fluoro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine
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