8-Hydroxy Naltrexone

Name: 8-Hydroxy Naltrexone
Brand: Vaqora Chemicals
SKU: VQ-032061

About 8-Hydroxy Naltrexone

Listed under CAS 2139257-33-1, 8-Hydroxy Naltrexone is a metabolite or degradation product of Naltrexone available from Vaqora Chemicals. With the molecular formula C20H23NO5, it has a molar mass of 357.4 g/mol. It is also known as 8beta-Hydroxy Naltrexone or 8beta Hydroxy Naltrexone.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Naltrexone, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 8-Hydroxy Naltrexone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Naltrexone

View every impurity, metabolite and intermediate we list for Naltrexone.

Naltrexone impurities

Specifications & identifiers

Chemical identifiers
Product name	8-Hydroxy Naltrexone
Catalogue No.	VQ-032061
CAS Number	2139257-33-1
IUPAC name	(4R,4aS,5S,7aR,12bS)-3-(cyclopropylmethyl)-4a,5,9-trihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular formula	C₂₀H₂₃NO₅
Molecular weight	357.4 g/mol
Exact mass	357.1576
Grade	Reference Standard
HSN code	38229090
InChIKey	GEJUGVQZUBDPAB-KRUJCJHPSA-N
SMILES	C1CC1CN2CC[C@]34[C@@H]5C(=O)C[C@@H]([C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O)O
PubChem CID	71749201

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	3 / 6
TPSA	90.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 8-Hydroxy Naltrexone?

The CAS Registry Number of 8-Hydroxy Naltrexone is 2139257-33-1. It is also known as 8beta-Hydroxy Naltrexone, 8beta Hydroxy Naltrexone.

What is the molecular formula and molecular weight of 8-Hydroxy Naltrexone?

8-Hydroxy Naltrexone has the molecular formula C20H23NO5 and a molecular weight of 357.4 g/mol. Its IUPAC name is (4R,4aS,5S,7aR,12bS)-3-(cyclopropylmethyl)-4a,5,9-trihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one.

What is 8-Hydroxy Naltrexone used for?

8-Hydroxy Naltrexone is supplied as a characterised reference material related to Naltrexone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 8-Hydroxy Naltrexone can I order?

We supply 8-Hydroxy Naltrexone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 8-Hydroxy Naltrexone?

Yes. Every lot of 8-Hydroxy Naltrexone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 8-Hydroxy Naltrexone be shipped internationally?

Yes. We export 8-Hydroxy Naltrexone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.