Naltrexone 3-Acetate

Name: Naltrexone 3-Acetate
Brand: Vaqora Chemicals
SKU: VQ-026825

About Naltrexone 3-Acetate

Vaqora Chemicals supplies Naltrexone 3-Acetate, an impurity of Naltrexone registered under CAS number 111129-14-7. With the molecular formula C22H25NO5, it has a molar mass of 383.4 g/mol. It is also known as 3-(O)-Acetyl Naltrexone or 3-O-Acetylnaltrexone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Naltrexone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Naltrexone 3-Acetate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Naltrexone

View every impurity, metabolite and intermediate we list for Naltrexone.

Naltrexone impurities

Specifications & identifiers

Chemical identifiers
Product name	Naltrexone 3-Acetate
Catalogue No.	VQ-026825
CAS Number	111129-14-7
IUPAC name	[(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a-hydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-9-yl] acetate
Molecular formula	C₂₂H₂₅NO₅
Molecular weight	383.4 g/mol
Exact mass	383.1733
Grade	Reference Standard
HSN code	38229090
InChIKey	JLTNSYNVGULOOS-KDXIVRHGSA-N
SMILES	CC(=O)OC1=C2C3=C(C[C@@H]4[C@]5([C@]3(CCN4CC6CC6)[C@@H](O2)C(=O)CC5)O)C=C1
PubChem CID	5491711

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 6
TPSA	76.1 Å²
Synonyms	3-(O)-Acetyl Naltrexone, 3-O-Acetylnaltrexone, 3-O-Acetyl Naltrexone, Morphinan-6-one, 3-(acetyloxy)-17-(cyclopropylmethyl)-4,5-epoxy-3-hydroxy-, (5alpha)-, 14-O-Acetylnaltrexone, 17-(Cyclopropylmethyl)-14-hydroxy-6-oxo-5alpha-4,5-epoxymorphinan-3-yl acetate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naltrexone 3-Acetate?

The CAS Registry Number of Naltrexone 3-Acetate is 111129-14-7. It is also known as 3-(O)-Acetyl Naltrexone, 3-O-Acetylnaltrexone, 3-O-Acetyl Naltrexone.

What is the molecular formula and molecular weight of Naltrexone 3-Acetate?

Naltrexone 3-Acetate has the molecular formula C22H25NO5 and a molecular weight of 383.4 g/mol. Its IUPAC name is [(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a-hydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-9-yl] acetate.

What is Naltrexone 3-Acetate used for?

Naltrexone 3-Acetate is supplied as a characterised reference material related to Naltrexone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naltrexone 3-Acetate can I order?

We supply Naltrexone 3-Acetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naltrexone 3-Acetate?

Yes. Every lot of Naltrexone 3-Acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naltrexone 3-Acetate be shipped internationally?

Yes. We export Naltrexone 3-Acetate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.