Acalabrutinib WS

Name: Acalabrutinib WS
Brand: Vaqora Chemicals
SKU: VQ-007286

About Acalabrutinib WS

Acalabrutinib WS is a high-purity reference standard of Acalabrutinib carrying the CAS registry number 1420477-60-6. The compound has the formula C26H23N7O2, corresponding to a molecular weight of 465.5 g/mol. The IUPAC name is 4-[8-amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide. Common synonyms include Acalabrutanib Form-S and Acalabrutinib.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Acalabrutinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Acalabrutinib WS is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Acalabrutinib

View every impurity, metabolite and intermediate we list for Acalabrutinib.

Acalabrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Acalabrutinib WS
Catalogue No.	VQ-007286
CAS Number	1420477-60-6
IUPAC name	4-[8-amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide
Molecular formula	C₂₆H₂₃N₇O₂
Molecular weight	465.5 g/mol
Exact mass	465.1913
Grade	Reference Standard
HSN code	38229090
InChIKey	WDENQIQQYWYTPO-IBGZPJMESA-N
SMILES	CC#CC(=O)N1CCC[C@H]1C2=NC(=C3N2C=CN=C3N)C4=CC=C(C=C4)C(=O)NC5=CC=CC=N5
PubChem CID	71226662

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	2 / 6
TPSA	119 Å²
Synonyms	Acalabrutanib Form-S, Acalabrutinib, ACP 196, Calquence, ACP-196, Bruton Tyrosine Kinase Inhibitor ACP-196, Acalabrutinib (ACP-196), Acalabrutinib(ACP196), Acalabrutinib (JAN/USAN/INN), Calquence (TN), Acalabrutinib (Standard)

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P319, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Acalabrutinib WS?

The CAS Registry Number of Acalabrutinib WS is 1420477-60-6. It is also known as Acalabrutanib Form-S, Acalabrutinib, ACP 196.

What is the molecular formula and molecular weight of Acalabrutinib WS?

Acalabrutinib WS has the molecular formula C26H23N7O2 and a molecular weight of 465.5 g/mol. Its IUPAC name is 4-[8-amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide.

What is Acalabrutinib WS used for?

Acalabrutinib WS is supplied as a characterised reference material related to Acalabrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acalabrutinib WS can I order?

We supply Acalabrutinib WS in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acalabrutinib WS?

Yes. Every lot of Acalabrutinib WS is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acalabrutinib WS be shipped internationally?

Yes. Acalabrutinib WS is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.