Acebutolol EP Impurity H

Name: Acebutolol EP Impurity H
Brand: Vaqora Chemicals
SKU: VQ-021406

About Acebutolol EP Impurity H

Acebutolol EP Impurity H is a pharmacopeial impurity of Acebutolol carrying the CAS registry number 1329613-31-1. With the molecular formula C27H34N2O7, it has a molar mass of 498.6 g/mol. Its systematic (IUPAC) name is N-[3-acetyl-4-[3-[2-acetyl-4-(butanoylamino)phenoxy]-2-hydroxypropoxy]phenyl]butanamide. It is also known as Acebutolol Hydrochloride - Impurity H or Acebutolol Impurity H.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Acebutolol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Acebutolol EP Impurity H in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Acebutolol

View every impurity, metabolite and intermediate we list for Acebutolol.

Acebutolol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Acebutolol EP Impurity H
Catalogue No.	VQ-021406
CAS Number	1329613-31-1
IUPAC name	N-[3-acetyl-4-[3-[2-acetyl-4-(butanoylamino)phenoxy]-2-hydroxypropoxy]phenyl]butanamide
Molecular formula	C₂₇H₃₄N₂O₇
Molecular weight	498.6 g/mol
Exact mass	498.2366
Grade	Reference Standard
HSN code	38229090
InChIKey	DSBONHQVMSZXNU-UHFFFAOYSA-N
SMILES	CCCC(=O)NC1=CC(=C(C=C1)OCC(COC2=C(C=C(C=C2)NC(=O)CCC)C(=O)C)O)C(=O)C
PubChem CID	71587977

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	3 / 7
TPSA	131 Å²
Synonyms	Acebutolol Hydrochloride - Impurity H, N,N'-(((2-hydroxypropane-1,3-diyl)bis(oxy))bis(3-acetyl-4,1-phenylene))dibutyramide, N,N'-(((2-Hydroxypropane-1,3-diyl)bis(oxy))-bis(3-acetyl-4,1-phenylene))dibutyramide, 1,3-Bis(2-acetyl- 4-butyramidophenoxy)-2-hydroxypropane, Acebutolol Impurity H, N,N'-((2-Hydroxypropane-1,3-diyl)bis(oxy(3-acetyl-1,4-phenylene)))dibutanamide, N,N'-[(2-Hydroxypropane-1,3-diyl)bis[oxy(3-acetyl-1,4-phenylene)]]dibutanamide, 1,3-Bis(2-acetyl-4-butyramidophenoxy)-2-hydroxypropane, Acebutolol Hydrochloride - Impurity H (Freebase), N,N'-{(2-Hydroxypropane-1,3-diyl)bis[oxy(3-acetyl-4,1-phenylene)]}dibutanamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Acebutolol EP Impurity H?

The CAS Registry Number of Acebutolol EP Impurity H is 1329613-31-1. It is also known as Acebutolol Hydrochloride - Impurity H, N,N'-(((2-hydroxypropane-1,3-diyl)bis(oxy))bis(3-acetyl-4,1-phenylene))dibutyramide, N,N'-(((2-Hydroxypropane-1,3-diyl)bis(oxy))-bis(3-acetyl-4,1-phenylene))dibutyramide.

What is the molecular formula and molecular weight of Acebutolol EP Impurity H?

Acebutolol EP Impurity H has the molecular formula C27H34N2O7 and a molecular weight of 498.6 g/mol. Its IUPAC name is N-[3-acetyl-4-[3-[2-acetyl-4-(butanoylamino)phenoxy]-2-hydroxypropoxy]phenyl]butanamide.

What is Acebutolol EP Impurity H used for?

Acebutolol EP Impurity H is supplied as a characterised reference material related to Acebutolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acebutolol EP Impurity H can I order?

We supply Acebutolol EP Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acebutolol EP Impurity H?

Yes. Every lot of Acebutolol EP Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acebutolol EP Impurity H be shipped internationally?

Yes. Acebutolol EP Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.