Acemetacin EP Impurity E

Name: Acemetacin EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-020718

About Acemetacin EP Impurity E

Acemetacin EP Impurity E is a pharmacopeial impurity of Acemetacin carrying the CAS registry number 75302-98-6. Its molecular formula is C25H26ClNO6 and its molecular weight is 471.9 g/mol. The IUPAC name is [2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl] 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate. Common synonyms include Acemetacin - Impurity E and tert-Butyl acemetacin.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Acemetacin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Acemetacin EP Impurity E is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Acemetacin

View every impurity, metabolite and intermediate we list for Acemetacin.

Acemetacin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Acemetacin EP Impurity E
Catalogue No.	VQ-020718
CAS Number	75302-98-6
IUPAC name	[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl] 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate
Molecular formula	C₂₅H₂₆ClNO₆
Molecular weight	471.9 g/mol
Exact mass	471.1449
Grade	Reference Standard
HSN code	38229090
InChIKey	FPYWWHOBBPHPFR-UHFFFAOYSA-N
SMILES	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCC(=O)OC(C)(C)C
PubChem CID	13388202

Physical properties
Physical form	Solid
LogP (XLogP3)	5.5
H-bond donors / acceptors	0 / 6
TPSA	83.8 Å²

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H311Toxic in contact with skin
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P262, P264, P270, P273, P280, P301 + P316, P302 + P352, P316, P321, P330, P361 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Acemetacin EP Impurity E?

The CAS Registry Number of Acemetacin EP Impurity E is 75302-98-6. It is also known as Acemetacin - Impurity E, tert-Butyl acemetacin, 2-tert-Butoxy-2-oxoethyl [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate.

What is the molecular formula and molecular weight of Acemetacin EP Impurity E?

Acemetacin EP Impurity E has the molecular formula C25H26ClNO6 and a molecular weight of 471.9 g/mol. Its IUPAC name is [2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl] 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate.

What is Acemetacin EP Impurity E used for?

Acemetacin EP Impurity E is supplied as a characterised reference material related to Acemetacin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Acemetacin EP Impurity E can I order?

We supply Acemetacin EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Acemetacin EP Impurity E?

Yes. Every lot of Acemetacin EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Acemetacin EP Impurity E be shipped internationally?

Yes. Acemetacin EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.