Afoxolaner

Name: Afoxolaner
Brand: Vaqora Chemicals
SKU: VQ-027228

About Afoxolaner

Vaqora Chemicals supplies Afoxolaner, an API impurity reference standard registered under CAS number 1093861-60-9. The compound has the formula C26H17ClF9N3O3, corresponding to a molecular weight of 625.9 g/mol. Alternative names: EX-A3267.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of the parent drug substance, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Afoxolaner is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	Afoxolaner
Catalogue No.	VQ-027228
CAS Number	1093861-60-9
IUPAC name	4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]naphthalene-1-carboxamide
Molecular formula	C₂₆H₁₇ClF₉N₃O₃
Molecular weight	625.9 g/mol
Exact mass	625.0815
Grade	Reference Standard
HSN code	38229090
InChIKey	OXDDDHGGRFRLEE-UHFFFAOYSA-N
SMILES	C1C(=NOC1(C2=CC(=CC(=C2)Cl)C(F)(F)F)C(F)(F)F)C3=CC=C(C4=CC=CC=C43)C(=O)NCC(=O)NCC(F)(F)F
PubChem CID	25154249

Physical properties
Physical form	Solid
LogP (XLogP3)	6.7
H-bond donors / acceptors	2 / 13
TPSA	79.8 Å²

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P273, P280, P318, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Afoxolaner?

The CAS Registry Number of Afoxolaner is 1093861-60-9. It is also known as EX-A3267.

What is the molecular formula and molecular weight of Afoxolaner?

Afoxolaner has the molecular formula C26H17ClF9N3O3 and a molecular weight of 625.9 g/mol. Its IUPAC name is 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]naphthalene-1-carboxamide.

Which grade and pack sizes of Afoxolaner can I order?

We supply Afoxolaner in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Afoxolaner?

Yes. Every lot of Afoxolaner is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Afoxolaner be shipped internationally?

Yes. Afoxolaner is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.