Alfacalcidol EP Impurity A

Name: Alfacalcidol EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-021486

About Alfacalcidol EP Impurity A

Alfacalcidol EP Impurity A is a pharmacopeial impurity of Alfacalcidol carrying the CAS registry number 65445-14-9. With the molecular formula C27H44O2, it has a molar mass of 400.6 g/mol. Common synonyms include trans-Alfacalcidol and 5,6-trans-Alfacalcidol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Alfacalcidol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Alfacalcidol EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Alfacalcidol

View every impurity, metabolite and intermediate we list for Alfacalcidol.

Alfacalcidol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Alfacalcidol EP Impurity A
Catalogue No.	VQ-021486
CAS Number	65445-14-9
IUPAC name	trans-(1R,3S,5E)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
Molecular formula	C₂₇H₄₄O₂
Molecular weight	400.6 g/mol
Exact mass	400.3341
Grade	Reference Standard
HSN code	38229090
InChIKey	OFHCOWSQAMBJIW-AOSUDXALSA-N
SMILES	C[C@H](CCCC(C)C)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C\3/C[C@H](C[C@@H](C3=C)O)O)C
PubChem CID	5283718

Physical properties
Physical form	Solid
LogP (XLogP3)	6.8
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²
Synonyms	trans-Alfacalcidol, (1-alpha,3-beta,5E,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, 9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, (1-alpha,3-beta,5E,7E)-, 9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, (1alpha,3beta,5E,7E)-, 9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, (1alpha,3beta,5E,7E)-(9CI), 5,6-trans-Alfacalcidol, (5E,7E)-(1S,3R)-9,10-seco-5,7,10(19)-cholestatriene-1,3-diol, 9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, (1a,3b,5E,7E)-, (1S,3R,5E,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol (trans-Alfacalcidol), (5E)-1alpha-hydroxycholecalciferol, (1R,3S,5Z,7E)-9,10-Secocholesta-5,7,10-triene-1,3-diol

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H311Toxic in contact with skin
H330Fatal if inhaled
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P262, P264, P270, P271, P280, P284, P301 + P316, P302 + P352, P304 + P340, P316, P319, P320, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Alfacalcidol EP Impurity A?

The CAS Registry Number of Alfacalcidol EP Impurity A is 65445-14-9. It is also known as trans-Alfacalcidol, (1-alpha,3-beta,5E,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, 9,10-Secocholesta-5,7,10(19)-triene-1,3-diol, (1-alpha,3-beta,5E,7E)-.

What is the molecular formula and molecular weight of Alfacalcidol EP Impurity A?

Alfacalcidol EP Impurity A has the molecular formula C27H44O2 and a molecular weight of 400.6 g/mol.

What is Alfacalcidol EP Impurity A used for?

Alfacalcidol EP Impurity A is supplied as a characterised reference material related to Alfacalcidol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Alfacalcidol EP Impurity A can I order?

We supply Alfacalcidol EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Alfacalcidol EP Impurity A?

Yes. Every lot of Alfacalcidol EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Alfacalcidol EP Impurity A be shipped internationally?

Yes. Alfacalcidol EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.