Alpha-Clofarabine

Name: Alpha-Clofarabine
Brand: Vaqora Chemicals
SKU: VQ-022229

About Alpha-Clofarabine

Vaqora Chemicals supplies Alpha-Clofarabine, an impurity of Clofarabine registered under CAS number 491594-60-6. Formula C10H11ClFN5O3, molecular weight 303.68 g/mol. The IUPAC name is 5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol. Alternative names: α-Clofarabine and Clofarabine Alpha Anomer.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Clofarabine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Alpha-Clofarabine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Clofarabine

View every impurity, metabolite and intermediate we list for Clofarabine.

Clofarabine impurities

Specifications & identifiers

Chemical identifiers
Product name	Alpha-Clofarabine
Catalogue No.	VQ-022229
CAS Number	491594-60-6
IUPAC name	5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
Molecular formula	C₁₀H₁₁ClFN₅O₃
Molecular weight	303.68 g/mol
Exact mass	303.0534
Grade	Reference Standard
HSN code	38229090
InChIKey	WDDPHFBMKLOVOX-UHFFFAOYSA-N
SMILES	C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)F)Cl)N
PubChem CID	354624

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	3 / 8
TPSA	119 Å²
Synonyms	α-Clofarabine, Clofarabine Alpha Anomer, 5-(6-amino-2-chloro-9-purinyl)-4-fluoro-2-(hydroxymethyl)-3-oxolanol, Clolar (Genzyme), Adenosine, 2-chloro-2'-deoxy-2'-fluoro-, Adenine, 2-chloro-9-(2-deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-, 5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol, (2R,3S)-5-(6-Amino-2-chloro-purin-9-yl)-4-fluoro-2-hydroxymethyl-tetrahydro-furan-3-ol, 5-(6-amino-2-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol, 5-(6-Amino-2-chloro-purin-9-yl)-4-fluoro-2-hydroxymethyl-tetrahydro-furan-3-ol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Alpha-Clofarabine?

The CAS Registry Number of Alpha-Clofarabine is 491594-60-6. It is also known as α-Clofarabine, Clofarabine Alpha Anomer, 5-(6-amino-2-chloro-9-purinyl)-4-fluoro-2-(hydroxymethyl)-3-oxolanol.

What is the molecular formula and molecular weight of Alpha-Clofarabine?

Alpha-Clofarabine has the molecular formula C10H11ClFN5O3 and a molecular weight of 303.68 g/mol. Its IUPAC name is 5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol.

What is Alpha-Clofarabine used for?

Alpha-Clofarabine is supplied as a characterised reference material related to Clofarabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Alpha-Clofarabine can I order?

We supply Alpha-Clofarabine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Alpha-Clofarabine?

Yes. Every lot of Alpha-Clofarabine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Alpha-Clofarabine be shipped internationally?

Yes. We export Alpha-Clofarabine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.