Clofarabine

Name: Clofarabine
Brand: Vaqora Chemicals
SKU: VQ-022228

About Clofarabine

Vaqora Chemicals supplies Clofarabine, a high-purity reference standard of Clofarabine registered under CAS number 123318-82-1. Formula C10H11ClFN5O3, molecular weight 303.68 g/mol. The IUPAC name is (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol. Common synonyms include Cl-F-Ara-A and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Clofarabine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Clofarabine

View every impurity, metabolite and intermediate we list for Clofarabine.

Clofarabine impurities

Specifications & identifiers

Chemical identifiers
Product name	Clofarabine
Catalogue No.	VQ-022228
CAS Number	123318-82-1
IUPAC name	(2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
Molecular formula	C₁₀H₁₁ClFN₅O₃
Molecular weight	303.68 g/mol
Exact mass	303.0534
Grade	Reference Standard
HSN code	38229090
InChIKey	WDDPHFBMKLOVOX-AYQXTPAHSA-N
SMILES	C1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F)Cl)N
PubChem CID	119182

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	3 / 8
TPSA	119 Å²
Synonyms	Cl-F-Ara-A, 2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine, 9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-, 2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine, 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, 2-chloro-9-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)adenine, 2-chloro-2'-fluoroarabino-2'-deoxyadenosine, 2-chloro-9-(2-deoxy-2-fluoroarabinofuranosyl)adenine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arbinofuranosyl)adenine, Cl-F-araA

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H341Suspected of causing genetic defects
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P316, P318, P319, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Clofarabine?

The CAS Registry Number of Clofarabine is 123318-82-1. It is also known as Cl-F-Ara-A, 2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine, 9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-.

What is the molecular formula and molecular weight of Clofarabine?

Clofarabine has the molecular formula C10H11ClFN5O3 and a molecular weight of 303.68 g/mol. Its IUPAC name is (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol.

What is Clofarabine used for?

Clofarabine is supplied as a characterised reference material related to Clofarabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Clofarabine can I order?

We supply Clofarabine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Clofarabine?

Yes. Every lot of Clofarabine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Clofarabine be shipped internationally?

Yes. Clofarabine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.