α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide
Synonyms: 2-Hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylacetamide · alpha-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide · "alpha-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide"
α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide (CAS 2088032-68-0) – Levothyroxine impurity standard. C15H11I4NO4, MW 776.87.
About α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide
Listed under CAS 2088032-68-0, α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide is a metabolite or degradation product of Levothyroxine available from Vaqora Chemicals. Its molecular formula is C15H11I4NO4 and its molecular weight is 776.87 g/mol. Its systematic (IUPAC) name is 2-hydroxy-2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylacetamide.
It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.
It is used in metabolite identification, stability-indicating method development and impurity profiling of Levothyroxine, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Vaqora Chemicals supplies α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.
Typical applications
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Industries
View every impurity, metabolite and intermediate we list for Levothyroxine.
Levothyroxine impuritiesSpecifications & identifiers
| Product name | α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide |
|---|---|
| Catalogue No. | VQ-043210 |
| CAS Number | 2088032-68-0 |
| IUPAC name | 2-hydroxy-2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylacetamide |
| Molecular formula | C15H11I4NO4 |
| Molecular weight | 776.87 g/mol |
| Exact mass | 776.6867 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | UBVLGDFYKKXFOZ-UHFFFAOYSA-N |
| SMILES | CNC(=O)C(C1=CC(=C(C(=C1)I)OC2=CC(=C(C(=C2)I)O)I)I)O |
| PubChem CID | 171370666 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 4.4 |
| H-bond donors / acceptors | 3 / 4 |
| TPSA | 78.8 Ų |
Documents
Frequently asked questions
What is the CAS number of α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide?
The CAS Registry Number of α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide is 2088032-68-0. It is also known as 2-Hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylacetamide, alpha-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide, "alpha-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide".
What is the molecular formula and molecular weight of α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide?
α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide has the molecular formula C15H11I4NO4 and a molecular weight of 776.87 g/mol. Its IUPAC name is 2-hydroxy-2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-N-methylacetamide.
What is α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide used for?
α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide can I order?
We supply α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide?
Yes. Every lot of α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide be shipped internationally?
Yes. We export α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about α-Hydroxy-4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-N-methyl-benzeneacetamide
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