Levothyroxine Methyl Ester

Name: Levothyroxine Methyl Ester
Brand: Vaqora Chemicals
SKU: VQ-043208

About Levothyroxine Methyl Ester

Listed under CAS 32180-11-3, Levothyroxine Methyl Ester is an impurity of Levothyroxine available from Vaqora Chemicals. Formula C16H13I4NO4, molecular weight 790.9 g/mol. The IUPAC name is methyl (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate. Alternative names: Levothyroxine and Thyroxine Methyl Ester.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Levothyroxine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Levothyroxine Methyl Ester is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine Methyl Ester
Catalogue No.	VQ-043208
CAS Number	32180-11-3
IUPAC name	methyl (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate
Molecular formula	C₁₆H₁₃I₄NO₄
Molecular weight	790.9 g/mol
Exact mass	790.7023
Grade	Reference Standard
HSN code	38229090
InChIKey	ZTSGDCMQRKBJKC-ZDUSSCGKSA-N
SMILES	COC(=O)[C@H](CC1=CC(=C(C(=C1)I)OC2=CC(=C(C(=C2)I)O)I)I)N
PubChem CID	13911218

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	2 / 5
TPSA	81.8 Å²
Synonyms	Levothyroxine, Methyl O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosinate, Thyroxine Methyl Ester, L-Thyroxine Methyl Ester, L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, methyl ester, (S)-Methyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate, Thyroxine methyl ester, L-, Methyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate, O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine Methyl Ester, 3,3',5,5'-Tetraiodo-thyro-methylester, (S)-Methyl2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate, methyl (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levothyroxine Methyl Ester?

The CAS Registry Number of Levothyroxine Methyl Ester is 32180-11-3. It is also known as Levothyroxine, Methyl O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosinate, Thyroxine Methyl Ester.

What is the molecular formula and molecular weight of Levothyroxine Methyl Ester?

Levothyroxine Methyl Ester has the molecular formula C16H13I4NO4 and a molecular weight of 790.9 g/mol. Its IUPAC name is methyl (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate.

What is Levothyroxine Methyl Ester used for?

Levothyroxine Methyl Ester is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine Methyl Ester can I order?

We supply Levothyroxine Methyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine Methyl Ester?

Yes. Every lot of Levothyroxine Methyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine Methyl Ester be shipped internationally?

Yes. We export Levothyroxine Methyl Ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.