Alpha-Yohimbine hydrochloride

Name: Alpha-Yohimbine hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-043652

About Alpha-Yohimbine hydrochloride

Alpha-Yohimbine hydrochloride (CAS 6211-32-1) is an impurity of Yohimbine offered by Vaqora Chemicals. The compound has the formula C21H27ClN2O3, corresponding to a molecular weight of 390.9 g/mol. Common synonyms include Rauwolscine hydrochloride and Rauwolscine HCl.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Yohimbine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Alpha-Yohimbine hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Yohimbine

View every impurity, metabolite and intermediate we list for Yohimbine.

Yohimbine impurities

Specifications & identifiers

Chemical identifiers
Product name	Alpha-Yohimbine hydrochloride
Catalogue No.	VQ-043652
CAS Number	6211-32-1
IUPAC name	methyl (1S,15S,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride
Molecular formula	C₂₁H₂₇ClN₂O₃
Molecular weight	390.9 g/mol
Exact mass	390.171
Grade	Reference Standard
HSN code	38229090
InChIKey	PIPZGJSEDRMUAW-ZKKXXTDSSA-N
SMILES	COC(=O)[C@@H]1[C@H](CC[C@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl
PubChem CID	197067

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 4
TPSA	65.6 Å²
Synonyms	Rauwolscine hydrochloride, Rauwolscine HCl, alpha-Yohimbin hydrochloride, 20-alpha-Yohimban-16-beta-carboxylic acid, 17-alpha-hydroxy-, methyl ester, hydrochloride, 20alpha-Yohimban-16beta-carboxylic acid, 17alpha-hydroxy-, methyl ester, monohydrochloride, Fauwolscine, hydrochloride, Methyl (16beta,17alpha,20alpha)-17-hydroxyyohimban-16-carboxylate hydrochloride, Rauwolscine (hydrochloride), Methyl 17alpha-hydroxy-20alpha-yohimban-16beta-carboxylate--hydrogen chloride (1/1)

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled

Precautionary statements: P261, P262, P264, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P316, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Alpha-Yohimbine hydrochloride?

The CAS Registry Number of Alpha-Yohimbine hydrochloride is 6211-32-1. It is also known as Rauwolscine hydrochloride, Rauwolscine HCl, alpha-Yohimbin hydrochloride.

What is the molecular formula and molecular weight of Alpha-Yohimbine hydrochloride?

Alpha-Yohimbine hydrochloride has the molecular formula C21H27ClN2O3 and a molecular weight of 390.9 g/mol.

What is Alpha-Yohimbine hydrochloride used for?

Alpha-Yohimbine hydrochloride is supplied as a characterised reference material related to Yohimbine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Alpha-Yohimbine hydrochloride can I order?

We supply Alpha-Yohimbine hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Alpha-Yohimbine hydrochloride?

Yes. Every lot of Alpha-Yohimbine hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Alpha-Yohimbine hydrochloride be shipped internationally?

Yes. Alpha-Yohimbine hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.