Yohimbine EP Impurity B

Name: Yohimbine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-035528

About Yohimbine EP Impurity B

Yohimbine EP Impurity B is a pharmacopeial impurity of Yohimbine carrying the CAS registry number 131-03-3. With the molecular formula C21H26N2O3, it has a molar mass of 354.4 g/mol. Its systematic (IUPAC) name is methyl (1S,15S,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate. Alternative names: Rauwolscine and alpha-Yohimbine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Yohimbine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Yohimbine EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Yohimbine

View every impurity, metabolite and intermediate we list for Yohimbine.

Yohimbine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Yohimbine EP Impurity B
Catalogue No.	VQ-035528
CAS Number	131-03-3
IUPAC name	methyl (1S,15S,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Molecular formula	C₂₁H₂₆N₂O₃
Molecular weight	354.4 g/mol
Exact mass	354.1943
Grade	Reference Standard
HSN code	38229090
InChIKey	BLGXFZZNTVWLAY-DIRVCLHFSA-N
SMILES	COC(=O)[C@@H]1[C@H](CC[C@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O
PubChem CID	643606

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 4
TPSA	65.6 Å²
Synonyms	Rauwolscine, alpha-Yohimbine, Corynanthidine, Isoyohimbine, Mesoyohimbine, methyl 17alpha-hydroxy-20alpha-yohimban-16beta-carboxylate, meso-Yohimbine, Methyl (16beta,17alpha,20alpha)-17-hydroxyyohimban-16-carboxylate, 17alpha-hydroxy-20alpha-yohimban-16beta-carboxylic acid methyl ester, 17-alpha-Hydroxy-20-alpha-yohimban-16-beta-carboxylic acid methyl ester, 20-alpha-Yohimban-16-beta-carboxylic acid, 17-alpha-hydroxy-, methyl ester, [3H]rauwolscine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Yohimbine EP Impurity B?

The CAS Registry Number of Yohimbine EP Impurity B is 131-03-3. It is also known as Rauwolscine, alpha-Yohimbine, Corynanthidine.

What is the molecular formula and molecular weight of Yohimbine EP Impurity B?

Yohimbine EP Impurity B has the molecular formula C21H26N2O3 and a molecular weight of 354.4 g/mol. Its IUPAC name is methyl (1S,15S,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate.

What is Yohimbine EP Impurity B used for?

Yohimbine EP Impurity B is supplied as a characterised reference material related to Yohimbine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Yohimbine EP Impurity B can I order?

We supply Yohimbine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Yohimbine EP Impurity B?

Yes. Every lot of Yohimbine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Yohimbine EP Impurity B be shipped internationally?

Yes. We export Yohimbine EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.