Amiloride EP Impurity B

Name: Amiloride EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-022148

About Amiloride EP Impurity B

Amiloride EP Impurity B is a pharmacopeial impurity of Amiloride carrying the CAS registry number 4878-36-8. With the molecular formula C5H5ClN4O2, it has a molar mass of 188.57 g/mol. Its systematic (IUPAC) name is 3,5-diamino-6-chloropyrazine-2-carboxylic acid. Alternative names: Amiloride EP Impurity B (Free Base) and 3,5-Diamino-6-chloro-pyrazine acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

This Amiloride impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Amiloride EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Amiloride

View every impurity, metabolite and intermediate we list for Amiloride.

Amiloride impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Amiloride EP Impurity B
Catalogue No.	VQ-022148
CAS Number	4878-36-8
IUPAC name	3,5-diamino-6-chloropyrazine-2-carboxylic acid
Molecular formula	C₅H₅ClN₄O₂
Molecular weight	188.57 g/mol
Exact mass	188.0101
Grade	Reference Standard
HSN code	38229090
InChIKey	OCSQJDAUOOHJEI-UHFFFAOYSA-N
SMILES	C1(=C(N=C(C(=N1)Cl)N)N)C(=O)O
PubChem CID	6452119

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	3 / 6
TPSA	115 Å²
Synonyms	Amiloride Hydrochloride Dihydrate - Impurity B, Amiloride EP Impurity B (Free Base), 3,5-Diamino-6-chloro-pyrazine acid, Pyrazinecarboxylic acid, 3,5-diamino-6-chloro-, 3,5-Diamino-6-chloro-2-pyrazinecarboxylic acid, 3,5-Diamino-6-chloropyrazinecarboxylic acid, 3,5-diamino-6-chloropyrazine-2-carboxylicacid, Hydrochlorothiazide Impurity 3, 3,5-diamino-6-chloropyrazinoic acid, Amiloride Hydrochloride Dihydrate Impurity B, 3,5-diamino-6-chloropyrazine-2carboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amiloride EP Impurity B?

The CAS Registry Number of Amiloride EP Impurity B is 4878-36-8. It is also known as Amiloride Hydrochloride Dihydrate - Impurity B, Amiloride EP Impurity B (Free Base), 3,5-Diamino-6-chloro-pyrazine acid.

What is the molecular formula and molecular weight of Amiloride EP Impurity B?

Amiloride EP Impurity B has the molecular formula C5H5ClN4O2 and a molecular weight of 188.57 g/mol. Its IUPAC name is 3,5-diamino-6-chloropyrazine-2-carboxylic acid.

What is Amiloride EP Impurity B used for?

Amiloride EP Impurity B is supplied as a characterised reference material related to Amiloride. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amiloride EP Impurity B can I order?

We supply Amiloride EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amiloride EP Impurity B?

Yes. Every lot of Amiloride EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amiloride EP Impurity B be shipped internationally?

Yes. Amiloride EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.