Amiodarone EP Impurity D

Name: Amiodarone EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-020783

About Amiodarone EP Impurity D

Amiodarone EP Impurity D is a pharmacopeial impurity of Amiodarone carrying the CAS registry number 1951-26-4. Formula C19H16I2O3, molecular weight 546.1 g/mol. Its systematic (IUPAC) name is (2-butyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodophenyl)methanone. It is also known as Amiodarone Hydrochloride EP Impurity D or Amiodarone Hydrochloride - Impurity D.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Amiodarone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Amiodarone EP Impurity D is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Amiodarone

View every impurity, metabolite and intermediate we list for Amiodarone.

Amiodarone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Amiodarone EP Impurity D
Catalogue No.	VQ-020783
CAS Number	1951-26-4
IUPAC name	(2-butyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodophenyl)methanone
Molecular formula	C₁₉H₁₆I₂O₃
Molecular weight	546.1 g/mol
Exact mass	545.9189
Grade	Reference Standard
HSN code	38229090
InChIKey	PNFMEGSMKIHDFZ-UHFFFAOYSA-N
SMILES	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)O)I
PubChem CID	74769

Physical properties
Physical form	Solid
LogP (XLogP3)	6.5
H-bond donors / acceptors	1 / 3
TPSA	50.4 Å²
Synonyms	Amiodarone Hydrochloride EP Impurity D, Amiodarone EP Impurity D, amiodarone USP Related Compound D, Amiodarone Hydrochloride - Impurity D, (2-Butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone, 2-butyl-3-(3,5-diiodo-4-hydroxy benzoyl) benzofuran, 2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran, (2-Butylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)methanone, 3-(4-Hydroxy-3,5-diiodo)-benzoyl-2-butyl benzofuran, (2-Butyl-benzofuran-3-yl)-(4-hydroxy-3,5-diiodo-phenyl)-methanone, Methanone, (2-butyl-3-benzofuranyl)(4-hydroxy-3,5-diiodophenyl)-, 2-Butyl-3-(4-hydroxy-3,5-diiodobenzoyl)benzofuran

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amiodarone EP Impurity D?

The CAS Registry Number of Amiodarone EP Impurity D is 1951-26-4. It is also known as Amiodarone Hydrochloride EP Impurity D, Amiodarone EP Impurity D, amiodarone USP Related Compound D.

What is the molecular formula and molecular weight of Amiodarone EP Impurity D?

Amiodarone EP Impurity D has the molecular formula C19H16I2O3 and a molecular weight of 546.1 g/mol. Its IUPAC name is (2-butyl-1-benzofuran-3-yl)-(4-hydroxy-3,5-diiodophenyl)methanone.

What is Amiodarone EP Impurity D used for?

Amiodarone EP Impurity D is supplied as a characterised reference material related to Amiodarone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amiodarone EP Impurity D can I order?

We supply Amiodarone EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amiodarone EP Impurity D?

Yes. Every lot of Amiodarone EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amiodarone EP Impurity D be shipped internationally?

Yes. Amiodarone EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.