Anastrozole EP Impurity E

Name: Anastrozole EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-021596

About Anastrozole EP Impurity E

Vaqora Chemicals supplies Anastrozole EP Impurity E, a pharmacopeial impurity of Anastrozole registered under CAS number 120511-88-8. The compound has the formula C15H18N2O, corresponding to a molecular weight of 242.32 g/mol. Systematically, it is named 2-[3-(2-cyanopropan-2-yl)-5-(hydroxymethyl)phenyl]-2-methylpropanenitrile. It is also known as Anastrozole - Impurity E or Anastrozole Impurity E.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Anastrozole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Anastrozole EP Impurity E is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Anastrozole

View every impurity, metabolite and intermediate we list for Anastrozole.

Anastrozole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Anastrozole EP Impurity E
Catalogue No.	VQ-021596
CAS Number	120511-88-8
IUPAC name	2-[3-(2-cyanopropan-2-yl)-5-(hydroxymethyl)phenyl]-2-methylpropanenitrile
Molecular formula	C₁₅H₁₈N₂O
Molecular weight	242.32 g/mol
Exact mass	242.1419
Grade	Reference Standard
HSN code	38229090
InChIKey	PLEAQICJSGOGID-UHFFFAOYSA-N
SMILES	CC(C)(C#N)C1=CC(=CC(=C1)CO)C(C)(C)C#N
PubChem CID	19349398

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 3
TPSA	67.8 Å²
Synonyms	Anastrozole - Impurity E, 1,3-Benzenediacetonitrile, 5-(hydroxymethyl)-alpha1,alpha1,alpha3,alpha3-tetramethyl-, 5-(Hydroxymethyl)-alpha1,alpha1,alpha3,alpha3-tetramethyl-1,3-benzenediacetonitrile, 5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile, 2,2'-(5-(hydroxymethyl)-1,3-phenylene)bis(2-methylpropanenitrile), 1,3-Benzenediacetonitrile, 5-(hydroxymethyl)-a1,a1,a3,a3-tetramethyl-, 2,2'-(5-(Hydroxymethyl)-1,3-phenylene)bis(2-methylpropanenitrile) (Anastrozole Impurity), 2,2'-[5-(Hydroxymethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile), 2,2-(5-(Hydroxymethyl)benzene-1,3-diyl)bis(2-methylpropanenitrile), 2-(3-(Cyanodimethylmethyl)-5-hydroxymethylphenyl)-2-methylpropionitrile, Anastrozole Impurity E, 2,2'-[5-(Hydroxymethyl)-1,3-phenylene]bis(2-methylpropanenitrile)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements: P261, P272, P280, P302 + P352, P321, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Anastrozole EP Impurity E?

The CAS Registry Number of Anastrozole EP Impurity E is 120511-88-8. It is also known as Anastrozole - Impurity E, 1,3-Benzenediacetonitrile, 5-(hydroxymethyl)-alpha1,alpha1,alpha3,alpha3-tetramethyl-, 5-(Hydroxymethyl)-alpha1,alpha1,alpha3,alpha3-tetramethyl-1,3-benzenediacetonitrile.

What is the molecular formula and molecular weight of Anastrozole EP Impurity E?

Anastrozole EP Impurity E has the molecular formula C15H18N2O and a molecular weight of 242.32 g/mol. Its IUPAC name is 2-[3-(2-cyanopropan-2-yl)-5-(hydroxymethyl)phenyl]-2-methylpropanenitrile.

What is Anastrozole EP Impurity E used for?

Anastrozole EP Impurity E is supplied as a characterised reference material related to Anastrozole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Anastrozole EP Impurity E can I order?

We supply Anastrozole EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Anastrozole EP Impurity E?

Yes. Every lot of Anastrozole EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Anastrozole EP Impurity E be shipped internationally?

Yes. Anastrozole EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.