Apixaban Tetrahydro Impurity

Name: Apixaban Tetrahydro Impurity
Brand: Vaqora Chemicals
SKU: VQ-004430

About Apixaban Tetrahydro Impurity

Apixaban Tetrahydro Impurity is an impurity of Apixaban carrying the CAS registry number 536759-91-8. Formula C22H20N4O6, molecular weight 436.4 g/mol. Its systematic (IUPAC) name is ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxylate. It is also known as Apixaban Related Compound F or Apixaban Impurity 102.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Apixaban to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Apixaban Tetrahydro Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Apixaban

View every impurity, metabolite and intermediate we list for Apixaban.

Apixaban impurities

Specifications & identifiers

Chemical identifiers
Product name	Apixaban Tetrahydro Impurity
Catalogue No.	VQ-004430
CAS Number	536759-91-8
IUPAC name	ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxylate
Molecular formula	C₂₂H₂₀N₄O₆
Molecular weight	436.4 g/mol
Exact mass	436.1383
Grade	Reference Standard
HSN code	38229090
InChIKey	RQNAOIQEGPVYTC-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=NN(C2=C1CCN(C2=O)C3=CC=C(C=C3)[N+](=O)[O-])C4=CC=C(C=C4)OC
PubChem CID	11711790

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	0 / 7
TPSA	119 Å²
Synonyms	Apixaban Related Compound F, Apixaban Impurity 102, Apixaban Impurity 44, CS-M0374, 4,5,6,7-Tetrahydro-1-(4-methoxyphe

Safety & hazard information (GHS)

Environmental hazard

Signal word: Warning

Hazard statements

H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P273, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Apixaban Tetrahydro Impurity?

The CAS Registry Number of Apixaban Tetrahydro Impurity is 536759-91-8. It is also known as Apixaban Related Compound F, Apixaban Impurity 102, Apixaban Impurity 44.

What is the molecular formula and molecular weight of Apixaban Tetrahydro Impurity?

Apixaban Tetrahydro Impurity has the molecular formula C22H20N4O6 and a molecular weight of 436.4 g/mol. Its IUPAC name is ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxylate.

What is Apixaban Tetrahydro Impurity used for?

Apixaban Tetrahydro Impurity is supplied as a characterised reference material related to Apixaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Apixaban Tetrahydro Impurity can I order?

We supply Apixaban Tetrahydro Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Apixaban Tetrahydro Impurity?

Yes. Every lot of Apixaban Tetrahydro Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Apixaban Tetrahydro Impurity be shipped internationally?

Yes. Apixaban Tetrahydro Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.