Apremilast Impurity 5

Name: Apremilast Impurity 5
Brand: Vaqora Chemicals
SKU: VQ-024334

About Apremilast Impurity 5

Listed under CAS 2095036-40-9, Apremilast Impurity 5 is an impurity of Apremilast available from Vaqora Chemicals. Formula C20H20N2O8S, molecular weight 448.4 g/mol. Systematically, it is named 2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-nitroisoindole-1,3-dione. It is also known as Nitro Apremilast or 4-Nitro Apremilast.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Apremilast, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Apremilast Impurity 5 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Apremilast

View every impurity, metabolite and intermediate we list for Apremilast.

Apremilast impurities

Specifications & identifiers

Chemical identifiers
Product name	Apremilast Impurity 5
Catalogue No.	VQ-024334
CAS Number	2095036-40-9
IUPAC name	2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-nitroisoindole-1,3-dione
Molecular formula	C₂₀H₂₀N₂O₈S
Molecular weight	448.4 g/mol
Exact mass	448.094
Grade	Reference Standard
HSN code	38229090
InChIKey	MQKGPVSCBKQSDG-OAHLLOKOSA-N
SMILES	CCOC1=C(C=CC(=C1)[C@@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)[N+](=O)[O-])OC
PubChem CID	89759314

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	0 / 8
TPSA	144 Å²
Synonyms	Nitro Apremilast, 2-((1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl)-4-nitroisoindole-1,3-dione, 4-Nitro Apremilast, Apremilast Impurity E, (S)-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-4-nitroisoindoline-1,3-dione, Apremilast Impurity 38

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P263, P264, P270, P272, P280, P301 + P317, P302 + P352, P318, P319, P321, P330, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Apremilast Impurity 5?

The CAS Registry Number of Apremilast Impurity 5 is 2095036-40-9. It is also known as Nitro Apremilast, 2-((1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl)-4-nitroisoindole-1,3-dione, 4-Nitro Apremilast.

What is the molecular formula and molecular weight of Apremilast Impurity 5?

Apremilast Impurity 5 has the molecular formula C20H20N2O8S and a molecular weight of 448.4 g/mol. Its IUPAC name is 2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-nitroisoindole-1,3-dione.

What is Apremilast Impurity 5 used for?

Apremilast Impurity 5 is supplied as a characterised reference material related to Apremilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Apremilast Impurity 5 can I order?

We supply Apremilast Impurity 5 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Apremilast Impurity 5?

Yes. Every lot of Apremilast Impurity 5 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Apremilast Impurity 5 be shipped internationally?

Yes. Apremilast Impurity 5 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.