Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer 170902-80-4

Name: Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer
Brand: Vaqora Chemicals
SKU: VQ-035081

About Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer

Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer (CAS 170902-80-4) is a metabolite or degradation product of Aprepitant offered by Vaqora Chemicals. Its molecular formula is C20H18F7NO2 and its molecular weight is 437.4 g/mol. The IUPAC name is (2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. Common synonyms include Fosaprepitant Morpholine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Aprepitant, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Aprepitant

View every impurity, metabolite and intermediate we list for Aprepitant.

Aprepitant impurities

Specifications & identifiers

Chemical identifiers
Product name	Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer
Catalogue No.	VQ-035081
CAS Number	170902-80-4
IUPAC name	(2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine
Molecular formula	C₂₀H₁₈F₇NO₂
Molecular weight	437.4 g/mol
Exact mass	437.1226
Grade	Reference Standard
HSN code	38229090
InChIKey	AFBDSAJOMZYQAI-VQTKTOELSA-N
SMILES	C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@H]2[C@@H](NCCO2)C3=CC=C(C=C3)F
PubChem CID	22860726

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	1 / 10
TPSA	30.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer?

The CAS Registry Number of Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer is 170902-80-4. It is also known as Fosaprepitant Morpholine, 2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine, (2S,3S)-.

What is the molecular formula and molecular weight of Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer?

Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer has the molecular formula C20H18F7NO2 and a molecular weight of 437.4 g/mol. Its IUPAC name is (2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine.

What is Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer used for?

Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer is supplied as a characterised reference material related to Aprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer can I order?

We supply Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer?

Yes. Every lot of Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer be shipped internationally?

Yes. We export Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.