(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate
- CAS
- 200000-59-5
- Formula
- C27H26F7NO5S
- MW
- 609.6 g/mol
VQ-047435
Impurity reference standards
Aprepitant impurities & reference standards
Characterised Aprepitant impurities, degradation products and related compounds for analytical method development, validation, QC release and regulatory filings.
41reference materials
1nitrosamine impurities
1isotope-labelled
COAHPLC · NMR · MS on request
Parent API: Aprepitant
170729-80-3 · C23H21F7N4O3
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride
- CAS
- 171482-05-6
- Formula
- C20H19ClF7NO2
- MW
- 473.8 g/mol
VQ-024343
(2R,3S)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine
- CAS
- 2377328-01-1
- Formula
- C27H24F7NO2
- MW
- 527.5 g/mol
VQ-035783
![(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone chemical structure](/media/structures/KVPJNHLVRGUYGQ-BFUOFWGJSA-N.svg)
(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone
- CAS
- 287930-75-0
- Formula
- C21H19F6NO3
- MW
- 447.4 g/mol
VQ-024350
(2R)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholin-3-ol
- CAS
- 1651828-04-4
- Formula
- C27H24F7NO3
- MW
- 543.5 g/mol
VQ-035784
![(5R,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone chemical structure](/media/structures/UISOBKKSNVFVOF-AQQIJUCISA-N.svg)
(5R,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone
- CAS
- 419574-33-7
- Formula
- C20H16F7NO3
- MW
- 451.3 g/mol
VQ-035082
(AlphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol
- CAS
- 127852-28-2
- Formula
- C10H8F6O
- MW
- 258.16 g/mol
VQ-029208
(R)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine
- CAS
- 380499-07-0
- Formula
- C20H16F7NO2
- MW
- 435.3 g/mol
VQ-029206
![2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine chemical structure](/media/structures/AFBDSAJOMZYQAI-FJNPEDAXSA-N.svg)
2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine
- CAS
- 170729-79-0
- Formula
- C20H18F7NO2
- MW
- 437.4 g/mol
VQ-024340
Aprepitant M2 Metabolite (1R,2R,3R)-Isomer Hydrochloride
- CAS
- 1447693-83-5
- Formula
- C20H19ClF7NO2
- MW
- 473.8 g/mol
VQ-035782
Aprepitant M2 Metabolite (1R,2S,3R)-Isomer Hydrochloride
- CAS
- 2475187-95-0
- Formula
- C20H19ClF7NO2
- MW
- 473.8 g/mol
VQ-047436
Aprepitant M2 Metabolite (1R,2S,3S)-Isomer Hydrochloride
- CAS
- 1333998-27-8
- Formula
- C20H19ClF7NO2
- MW
- 473.8 g/mol
VQ-047438
Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer HCl
- CAS
- 2475188-05-5
- Formula
- C20H19ClF7NO2
- MW
- 473.8 g/mol
VQ-035779
Aprepitant M2 Metabolite (1S,2R,3R)-Isomer Hydrochloride
- CAS
- 1333998-21-2
- Formula
- C20H19ClF7NO2
- MW
- 473.8 g/mol
VQ-047437
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant
- CAS
- 327623-37-0
- Formula
- C20H18F7NO2
- MW
- 437.4 g/mol
VQ-035141
N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant
- CAS
- 219821-37-1
- Formula
- C24H25F7N4O4
- MW
- 566.5 g/mol
VQ-024346
FAQs — Aprepitant impurities
Which Aprepitant impurities do you supply?
We list 41 Aprepitant-related reference materials, including process impurities, degradation products, nitrosamine impurities, stable-isotope-labelled standards and related compounds. Each is supplied with a COA, and characterisation data (HPLC, 1H-NMR, MS, IR) can be provided on request.
What are Aprepitant impurity standards used for?
They are used for analytical method development and validation, impurity identification and quantification, forced-degradation and stability studies, and to support ANDA, DMF and other regulatory submissions under ICH Q3A/Q3B (and ICH M7 for mutagenic impurities).
Can you synthesise a Aprepitant impurity that is not listed?
Yes. Our custom synthesis service can prepare and characterise unlisted impurities, metabolites and labelled analogues from milligram to gram scale. Share the structure or name and required quantity for a quotation.
Request Aprepitant impurity standards
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