Articaine EP Impurity E

Name: Articaine EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-021627

About Articaine EP Impurity E

Articaine EP Impurity E (CAS 1796888-45-3) is a pharmacopeial impurity of Articaine offered by Vaqora Chemicals. With the molecular formula C13H20N2O3S, it has a molar mass of 284.38 g/mol. Systematically, it is named methyl 4-methyl-3-[2-(propan-2-ylamino)propanoylamino]thiophene-2-carboxylate. It is also known as Articaine Related Compound E or isopropylarticaine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Articaine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Articaine EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Articaine

View every impurity, metabolite and intermediate we list for Articaine.

Articaine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Articaine EP Impurity E
Catalogue No.	VQ-021627
CAS Number	1796888-45-3
IUPAC name	methyl 4-methyl-3-[2-(propan-2-ylamino)propanoylamino]thiophene-2-carboxylate
Molecular formula	C₁₃H₂₀N₂O₃S
Molecular weight	284.38 g/mol
Exact mass	284.1195
Grade	Reference Standard
HSN code	38229090
InChIKey	MHGQFYHUUMZHET-UHFFFAOYSA-N
SMILES	CC1=CSC(=C1NC(=O)C(C)NC(C)C)C(=O)OC
PubChem CID	121230774

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 5
TPSA	95.7 Å²
Synonyms	Articaine Related Compound E, methyl 4-methyl-3-{2-[(propan-2-yl)amino]propanamido}thiophene-2-carboxylate, Methyl 4-methyl-3-(2-((propan-2-yl)amino)propanamido)thiophene-2-carboxylate, isopropylarticaine, Articaine Impurity E, Methyl 3-(2-(isopropylamino)propanamido)-4-methylthiophene-2-carboxylate, Isopropylarticaine HCl, Methyl 3-[2-(Isopropylamino)propanamido]-4-methylthiophene-2-carboxylate, Methyl3-(2-(isopropylamino)propanamido)-4-methylthiophene-2-carboxylate, methyl 3-[2-(isopropylamino)propanoylamino]-4-methyl-thiophene-2-carboxylate, Methyl 4-methyl-3-[[2-[(1-methylethyl)amino]-1-oxopropyl]amino]-2-thiophenecarboxylate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Articaine EP Impurity E?

The CAS Registry Number of Articaine EP Impurity E is 1796888-45-3. It is also known as Articaine Related Compound E, methyl 4-methyl-3-{2-[(propan-2-yl)amino]propanamido}thiophene-2-carboxylate, Methyl 4-methyl-3-(2-((propan-2-yl)amino)propanamido)thiophene-2-carboxylate.

What is the molecular formula and molecular weight of Articaine EP Impurity E?

Articaine EP Impurity E has the molecular formula C13H20N2O3S and a molecular weight of 284.38 g/mol. Its IUPAC name is methyl 4-methyl-3-[2-(propan-2-ylamino)propanoylamino]thiophene-2-carboxylate.

What is Articaine EP Impurity E used for?

Articaine EP Impurity E is supplied as a characterised reference material related to Articaine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Articaine EP Impurity E can I order?

We supply Articaine EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Articaine EP Impurity E?

Yes. Every lot of Articaine EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Articaine EP Impurity E be shipped internationally?

Yes. Articaine EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.