Asciminib

Name: Asciminib
Brand: Vaqora Chemicals
SKU: VQ-007324

About Asciminib

Asciminib (CAS 1492952-76-7) is a high-purity reference standard of Asciminib offered by Vaqora Chemicals. The compound has the formula C20H18ClF2N5O3, corresponding to a molecular weight of 449.8 g/mol. It is also known as Scemblix or ABL 001NX.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Asciminib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Asciminib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Asciminib

View every impurity, metabolite and intermediate we list for Asciminib.

Asciminib impurities

Specifications & identifiers

Chemical identifiers
Product name	Asciminib
Catalogue No.	VQ-007324
CAS Number	1492952-76-7
Other CAS	2119669-71-3, 2679814-62-9
IUPAC name	N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide
Molecular formula	C₂₀H₁₈ClF₂N₅O₃
Molecular weight	449.8 g/mol
Exact mass	449.1066
Grade	Reference Standard
HSN code	38229090
InChIKey	VOVZXURTCKPRDQ-CQSZACIVSA-N
SMILES	C1CN(C[C@@H]1O)C2=C(C=C(C=N2)C(=O)NC3=CC=C(C=C3)OC(F)(F)Cl)C4=CC=NN4
PubChem CID	72165228

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	3 / 8
TPSA	103 Å²
Synonyms	Scemblix, ABL 001NX, ABL-001, Asciminib free base, Asciminib (ABL001), Example 9, AY7, C20H18ClF2N5O3, Asciminib (Standard), 1492952-76-7 (free base), Asciminib (USAN/INN), EX-A3030

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Asciminib?

The CAS Registry Number of Asciminib is 1492952-76-7. It is also known as Scemblix, ABL 001NX, ABL-001.

What is the molecular formula and molecular weight of Asciminib?

Asciminib has the molecular formula C20H18ClF2N5O3 and a molecular weight of 449.8 g/mol. Its IUPAC name is N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide.

What is Asciminib used for?

Asciminib is supplied as a characterised reference material related to Asciminib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Asciminib can I order?

We supply Asciminib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Asciminib?

Yes. Every lot of Asciminib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Asciminib be shipped internationally?

Yes. We export Asciminib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.