Asciminib Impurity 2

Name: Asciminib Impurity 2
Brand: Vaqora Chemicals
SKU: VQ-045284

About Asciminib Impurity 2

Asciminib Impurity 2 is an impurity of Asciminib carrying the CAS registry number 1492954-67-2. The compound has the formula C25H26ClF2N5O4, corresponding to a molecular weight of 534.0 g/mol. It is also known as Asciminib THP Protected Impurity or Asciminib Tetrahydropyranyl Impurity.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Asciminib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Asciminib

View every impurity, metabolite and intermediate we list for Asciminib.

Asciminib impurities

Specifications & identifiers

Chemical identifiers
Product name	Asciminib Impurity 2
Catalogue No.	VQ-045284
CAS Number	1492954-67-2
IUPAC name	N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-[2-(oxan-2-yl)pyrazol-3-yl]pyridine-3-carboxamide
Molecular formula	C₂₅H₂₆ClF₂N₅O₄
Molecular weight	534 g/mol
Exact mass	533.1641
Grade	Reference Standard
HSN code	38229090
InChIKey	DMOJSBXYOKHSRX-ZZWBGTBQSA-N
SMILES	C1CCOC(C1)N2C(=CC=N2)C3=C(N=CC(=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)Cl)N5CC[C@H](C5)O
PubChem CID	72545855

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	2 / 9
TPSA	102 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Asciminib Impurity 2?

The CAS Registry Number of Asciminib Impurity 2 is 1492954-67-2. It is also known as Asciminib THP Protected Impurity, Asciminib Tetrahydropyranyl Impurity.

What is the molecular formula and molecular weight of Asciminib Impurity 2?

Asciminib Impurity 2 has the molecular formula C25H26ClF2N5O4 and a molecular weight of 534 g/mol. Its IUPAC name is N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-[2-(oxan-2-yl)pyrazol-3-yl]pyridine-3-carboxamide.

What is Asciminib Impurity 2 used for?

Asciminib Impurity 2 is supplied as a characterised reference material related to Asciminib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Asciminib Impurity 2 can I order?

We supply Asciminib Impurity 2 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Asciminib Impurity 2?

Yes. Every lot of Asciminib Impurity 2 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Asciminib Impurity 2 be shipped internationally?

Yes. We export Asciminib Impurity 2 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.